% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Nimerovsky:1026616,
      author       = {Nimerovsky, Evgeny and Sieme, Daniel and Rezaie Ghaleh,
                      Nasrollah},
      title        = {{M}obility of sodium ions in agarose gels probed through
                      combined single- and triple-quantum {NMR}},
      journal      = {Methods},
      volume       = {228},
      issn         = {1046-2023},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2024-03470},
      pages        = {55-64},
      year         = {2024},
      abstract     = {Metal ions, including biologically prevalent sodium ions,
                      can modulate electrostatic interactions frequently involved
                      in the stability of condensed compartments in cells.
                      Quantitative characterization of heterogeneous ion dynamics
                      inside biomolecular condensates demands new experimental
                      approaches. Here we develop a 23Na NMR relaxation-based
                      integrative approach to probe dynamics of sodium ions inside
                      agarose gels as a model system. We exploit the electric
                      quadrupole moment of spin-3/2 23Na nuclei and, through
                      combination of single-quantum and triple-quantum-filtered
                      23Na NMR relaxation methods, disentangle the relaxation
                      contribution of different populations of sodium ions inside
                      gels. Three populations of sodium ions are identified: a
                      population with biexponential relaxation representing ions
                      within the slow motion regime and wo populations with
                      monoexponential relaxation but at different rates. Our study
                      demonstrates the dynamical heterogeneity of sodium ions
                      inside agarose gels and presents a new experimental approach
                      for monitoring dynamics of sodium and other spin-3/2 ions
                      (e.g. chloride) in condensed environments.},
      cin          = {IBI-7},
      ddc          = {540},
      cid          = {I:(DE-Juel1)IBI-7-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5241},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {38782295},
      UT           = {WOS:001265960700001},
      doi          = {10.1016/j.ymeth.2024.05.015},
      url          = {https://juser.fz-juelich.de/record/1026616},
}