%0 Journal Article
%A Ray, Debes
%A Madani, M.
%A Dhont, Jan K. G.
%A Platten, Florian
%A Kang, Kyongok
%T The Effects of Electric Fields on Protein Phase Behavior and Protein Crystallization Kinetics
%J The journal of physical chemistry letters
%V 15
%@ 1948-7185
%C Washington, DC
%I ACS
%M FZJ-2024-05143
%P 8108 - 8113
%D 2024
%X We experimentally studied the effects of an externally applied electric field on protein crystallization and liquid–liquid phase separation (LLPS) and its crystallization kinetics. For a surprisingly weak alternating current (AC) electric field, crystallization was found to occur in a wider region of the phase diagram, while nucleation induction times were reduced, and crystal growth rates were enhanced. LLPS on the contrary was suppressed, which diminishes the tendency for a two-step crystallization scenario. The effect of the electric field is ascribed to a change in the protein–protein interaction potential.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ 39087873
%U <Go to ISI:>//WOS:001282974800001
%R 10.1021/acs.jpclett.4c01744
%U https://juser.fz-juelich.de/record/1029468