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100 1 _ |a Ray, Debes
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245 _ _ |a The Effects of Electric Fields on Protein Phase Behavior and Protein Crystallization Kinetics
260 _ _ |a Washington, DC
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520 _ _ |a We experimentally studied the effects of an externally applied electric field on protein crystallization and liquid–liquid phase separation (LLPS) and its crystallization kinetics. For a surprisingly weak alternating current (AC) electric field, crystallization was found to occur in a wider region of the phase diagram, while nucleation induction times were reduced, and crystal growth rates were enhanced. LLPS on the contrary was suppressed, which diminishes the tendency for a two-step crystallization scenario. The effect of the electric field is ascribed to a change in the protein–protein interaction potential.
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700 1 _ |a Dhont, Jan K. G.
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700 1 _ |a Platten, Florian
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700 1 _ |a Kang, Kyongok
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