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024 | 7 | _ | |a 10.1021/acs.jpclett.4c01744 |2 doi |
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100 | 1 | _ | |a Ray, Debes |0 P:(DE-Juel1)184311 |b 0 |e First author |
245 | _ | _ | |a The Effects of Electric Fields on Protein Phase Behavior and Protein Crystallization Kinetics |
260 | _ | _ | |a Washington, DC |c 2024 |b ACS |
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520 | _ | _ | |a We experimentally studied the effects of an externally applied electric field on protein crystallization and liquid–liquid phase separation (LLPS) and its crystallization kinetics. For a surprisingly weak alternating current (AC) electric field, crystallization was found to occur in a wider region of the phase diagram, while nucleation induction times were reduced, and crystal growth rates were enhanced. LLPS on the contrary was suppressed, which diminishes the tendency for a two-step crystallization scenario. The effect of the electric field is ascribed to a change in the protein–protein interaction potential. |
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536 | _ | _ | |a DFG project 495795796 - Das Phasenverhalten von Proteinlösungen in elektrischen Feldern (495795796) |0 G:(GEPRIS)495795796 |c 495795796 |x 1 |
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700 | 1 | _ | |a Madani, M. |0 P:(DE-HGF)0 |b 1 |
700 | 1 | _ | |a Dhont, Jan K. G. |0 P:(DE-Juel1)130616 |b 2 |
700 | 1 | _ | |a Platten, Florian |0 P:(DE-Juel1)180761 |b 3 |e Corresponding author |
700 | 1 | _ | |a Kang, Kyongok |0 P:(DE-Juel1)130749 |b 4 |e Corresponding author |
773 | _ | _ | |a 10.1021/acs.jpclett.4c01744 |g p. 8108 - 8113 |0 PERI:(DE-600)2522838-9 |p 8108 - 8113 |t The journal of physical chemistry letters |v 15 |y 2024 |x 1948-7185 |
856 | 4 | _ | |u https://pubs.acs.org/doi/10.1021/acs.jpclett.4c01744 |
856 | 4 | _ | |u https://juser.fz-juelich.de/record/1029468/files/ray-et-al-2024-the-effects-of-electric-fields-on-protein-phase-behavior-and-protein-crystallization-kinetics.pdf |y OpenAccess |z StatID:(DE-HGF)0510 |
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