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@INPROCEEDINGS{Nicolaisen:1030940,
      author       = {Nicolaisen, Eliana and GENON, Sarah},
      title        = {{T}he replicability crisis and the multivariate perspective
                      in mapping brain structure to behavioral phenotype},
      reportid     = {FZJ-2024-05531},
      year         = {2024},
      abstract     = {“What are the brain structural correlates of
                      interindividual differences in behaviour?” More than a
                      decade ago, advances in structural MRI opened promising
                      perspectives to address this question. In our work, we
                      haveinvestigated the replicability of associations between
                      local measurements of neuroanatomy and isolated behavioural
                      variables, including personality measures. Across
                      subsampling within large opendatasets (such the NKI and HCP
                      datasets), we generally found very low replicability rates.
                      Given these replicability issues that were also highlighted
                      in other studies and broadening scepticisms regarding
                      theidea of one-to-one mappings between psychological
                      constructs and brain regions, new perspectives embracing the
                      multivariate nature of structural brain-behaviour
                      relationships emerged. In our more recentwork, we
                      illustrated how multivariate approaches in large datasets
                      (such as the HCP datasets) can reveal complex, but robust,
                      patterns of brain-behaviour relationships spanning across
                      behavioral domains (fromcognitive measures to
                      personality-related measures) in the population data.},
      month         = {Aug},
      date          = {2024-08-06},
      organization  = {21st European Conference on
                       Personality, Berlin (Germany), 6 Aug
                       2024 - 8 Aug 2024},
      subtyp        = {Invited},
      cin          = {INM-7},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525) / 5252 - Brain Dysfunction and Plasticity
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251 / G:(DE-HGF)POF4-5252},
      typ          = {PUB:(DE-HGF)6},
      url          = {https://juser.fz-juelich.de/record/1030940},
}