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@INPROCEEDINGS{Grundmann:1034034,
      author       = {Grundmann, Lena and Müller-Linow, Mark and Kuhn, Arnd and
                      He, Fang and Schlehuber, Dennis and Keuter, Volkmar and
                      Noll, Gundula and Prüfer, Dirk},
      title        = {{E}tablierung von {Z}ell- und {G}ewebekulturen für
                      {M}edizinalpflanzen am {B}eispiel von {A}rnica montana im
                      {R}ahmen des {P}rojekts „{C}ircular {P}hyto{REVIER}“ –
                      {I}ntegrierte {W}ertschöpfung mit {A}nbau und {V}erwertung
                      von {M}edizinalpflanzen im {R}heinischen {R}evier},
      publisher    = {Bundesbehörden und Einrichtungen im Geschäftsbereich des
                      Bundesministeriums für Ernährung und Landwirtschaft
                      (BMEL)},
      reportid     = {FZJ-2024-06864},
      pages        = {35-43},
      year         = {2023},
      comment      = {Julius-Kühn-Archiv, vol. 4769. Tagung für Arznei- und
                      Gewürzpflanzenforschung : Sicherheit vom Anbau bis zum
                      Verbraucher – Spitzenklasse oder auf die Spitze getrieben?
                      ; Freising, 11. - 14. September 2023 ; Kurzfassungen der
                      Vorträge und Poster, p. 35},
      booktitle     = {Julius-Kühn-Archiv, vol. 4769. Tagung
                       für Arznei- und
                       Gewürzpflanzenforschung : Sicherheit
                       vom Anbau bis zum Verbraucher –
                       Spitzenklasse oder auf die Spitze
                       getrieben? ; Freising, 11. - 14.
                       September 2023 ; Kurzfassungen der
                       Vorträge und Poster, p. 35},
      abstract     = {Developing sustainable cultivation methods for medicinal
                      plants to meet the growing demand for high-quality raw
                      materials is of great importance to the pharmaceutical
                      industry. At the same time, it is important to minimize
                      environmental impact and protect biodiversity. As part of
                      the BioeconomyREVIER initiative to manage the structural
                      change resulting from the phase-out of lignite, the Rhenish
                      mining area is to be developed into a model region for a
                      sustainable bioeconomy. To this end, projects are being
                      supported in which innovative solutions are developed and
                      implemented in the form of innovation labs through close
                      cooperation between science and industry. One example is the
                      “Circular PhytoREVIER“ project, which focuses on
                      sustainable value creation with medicinal plants in the
                      Rhenish mining area. The three scientific partners involved,
                      Fraunhofer IME, Fraunhofer UMSICHT and Forschungszentrum
                      Jülich, IBG-2, have combined their respective expertise,
                      resources, infrastructures and preliminary work to establish
                      yield- and location-optimized medicinal plants and to
                      cultivate them both in the field and in closed indoor
                      systems. We develop innovative methods for the targeted
                      control and increase of the active ingredient content
                      through the application of biological, chemical and physical
                      stresses as well as for the non-invasive determination of
                      growth and harvest parameters. The work of the Fraunhofer
                      IME in this context includes the development of molecular
                      markers for breeding and the generation of cell and tissue
                      cultures of selected medicinal plants. One of our model
                      plants is Arnica montana, which produces sesquiterpene
                      lactones (SL) as valuable compounds. Our work has initially
                      focused on the identification of the previously unknown SL
                      biosynthetic genes and, in the future, on their
                      characterization. For this purpose, we are currently
                      focusing on the establishment of in vitro propagation of
                      arnica plants, as well as plant regeneration from single
                      cells, and finally on the genetic modification of Arnica
                      montana in order to be able to characterize the biosynthetic
                      genes of the SL metabolism in the future and to optimize the
                      SL content in the plant or in cell culture.},
      month         = {Sep},
      date          = {2023-09-11},
      organization  = {9. Tagung für Arznei- und
                       Gewürzpflanzenforschung, Freising
                       (Germany), 11 Sep 2023 - 14 Sep 2023},
      keywords     = {Medizinalpflanzen (Other) / Bioökonomie (Other) /
                      Genomeditierung (Other) / nicht-invasive Sensorik (Other) /
                      Pflanzenphänotypisierung (Other) / Zell- und Gewebekulturen
                      (Other) / Pflanzentransformation (Other) / medicinal plants
                      (Other) / bioeconomy (Other) / genome editing (Other) /
                      non-invasive sensors (Other) / plant phenotyping (Other) /
                      cell and tissue culture (Other) / plant transformation
                      (Other) / 630 (Other)},
      cin          = {IBG-2},
      cid          = {I:(DE-Juel1)IBG-2-20101118},
      pnm          = {2171 - Biological and environmental resources for
                      sustainable use (POF4-217)},
      pid          = {G:(DE-HGF)POF4-2171},
      typ          = {PUB:(DE-HGF)8 / PUB:(DE-HGF)7},
      doi          = {10.5073/20230821-142037-0},
      url          = {https://juser.fz-juelich.de/record/1034034},
}