001043478 001__ 1043478
001043478 005__ 20250820202246.0
001043478 0247_ $$2doi$$a10.1002/ana.27250
001043478 0247_ $$2ISSN$$a0364-5134
001043478 0247_ $$2ISSN$$a1531-8249
001043478 0247_ $$2datacite_doi$$a10.34734/FZJ-2025-02881
001043478 0247_ $$2pmid$$a40285625
001043478 0247_ $$2WOS$$aWOS:001475946300001
001043478 037__ $$aFZJ-2025-02881
001043478 082__ $$a610
001043478 1001_ $$0P:(DE-Juel1)196964$$aMüller, Laura$$b0$$ufzj
001043478 245__ $$aElevated α‐Synuclein Aggregate Levels in the Urine of Patients with Isolated REM Sleep Behavior Disorder and Parkinson's Disease
001043478 260__ $$aHoboken, NJ$$bWiley-Blackwell$$c2025
001043478 3367_ $$2DRIVER$$aarticle
001043478 3367_ $$2DataCite$$aOutput Types/Journal article
001043478 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1750932981_5558
001043478 3367_ $$2BibTeX$$aARTICLE
001043478 3367_ $$2ORCID$$aJOURNAL_ARTICLE
001043478 3367_ $$00$$2EndNote$$aJournal Article
001043478 520__ $$aParkinson's disease (PD) is a neurodegenerative disorder characterized by α‐synuclein aggregation in neurons. Recent advances suggest α‐synuclein aggregates could serve as a biomarker for PD and related synucleinopathies. This study used surface‐based fluorescence intensity distribution analysis (sFIDA) to measure α‐synuclein aggregates in urine. Patients with PD and isolated rapid eye movement sleep behavior disorder, a precursor to PD, had elevated concentrations compared with healthy controls. Sensitivity and specificity were 83% and 65% for PD versus controls and 89% and 62% for isolated rapid eye movement sleep behavior disorder versus controls. The findings highlight sFIDA's potential for diagnosing synucleinopathies. ANN NEUROL 2025;98:147–151
001043478 536__ $$0G:(DE-HGF)POF4-5244$$a5244 - Information Processing in Neuronal Networks (POF4-524)$$cPOF4-524$$fPOF IV$$x0
001043478 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
001043478 7001_ $$0P:(DE-Juel1)187484$$aÖzdüzenciler, Pelin$$b1
001043478 7001_ $$0P:(DE-HGF)0$$aSchedlich-Teufer, Charlotte$$b2
001043478 7001_ $$0P:(DE-Juel1)184882$$aSeger, Aline$$b3
001043478 7001_ $$00000-0003-3041-1583$$aJergas, Hannah$$b4
001043478 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b5$$ufzj
001043478 7001_ $$0P:(DE-Juel1)132029$$aWillbold, Dieter$$b6
001043478 7001_ $$0P:(DE-Juel1)179044$$aSommerauer, Michael$$b7
001043478 7001_ $$0P:(DE-Juel1)131613$$aBarbe, Michael T.$$b8
001043478 7001_ $$0P:(DE-Juel1)177986$$aTamgüney, Gültekin$$b9$$eCorresponding author
001043478 773__ $$0PERI:(DE-600)2037912-2$$a10.1002/ana.27250$$gVol. 98, no. 1, p. 147 - 151$$n1$$p147 - 151$$tAnnals of neurology$$v98$$x0364-5134$$y2025
001043478 8564_ $$uhttps://juser.fz-juelich.de/record/1043478/files/Annals%20of%20Neurology%20-%202025%20-%20M%C3%BCller%20-%20Elevated%20%E2%80%90Synuclein%20Aggregate%20Levels%20in%20the%20Urine%20of%20Patients%20with%20Isolated%20REM.pdf$$yOpenAccess
001043478 8767_ $$d2025-08-20$$eHybrid-OA$$jDEAL
001043478 909CO $$ooai:juser.fz-juelich.de:1043478$$pVDB$$pdriver$$pOpenAPC_DEAL$$popen_access$$popenaire$$popenCost$$pdnbdelivery
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)196964$$aForschungszentrum Jülich$$b0$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)187484$$aForschungszentrum Jülich$$b1$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)184882$$aForschungszentrum Jülich$$b3$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich$$b5$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)132029$$aForschungszentrum Jülich$$b6$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)179044$$aForschungszentrum Jülich$$b7$$kFZJ
001043478 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)177986$$aForschungszentrum Jülich$$b9$$kFZJ
001043478 9131_ $$0G:(DE-HGF)POF4-524$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5244$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vMolecular and Cellular Information Processing$$x0
001043478 9141_ $$y2025
001043478 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bANN NEUROL : 2022$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bANN NEUROL : 2022$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2024-12-18$$wger
001043478 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-18
001043478 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
001043478 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001043478 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2024-12-18
001043478 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2024-12-18$$wger
001043478 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-18
001043478 915pc $$0PC:(DE-HGF)0000$$2APC$$aAPC keys set
001043478 915pc $$0PC:(DE-HGF)0001$$2APC$$aLocal Funding
001043478 915pc $$0PC:(DE-HGF)0002$$2APC$$aDFG OA Publikationskosten
001043478 915pc $$0PC:(DE-HGF)0120$$2APC$$aDEAL: Wiley 2019
001043478 920__ $$lyes
001043478 9201_ $$0I:(DE-Juel1)IBI-7-20200312$$kIBI-7$$lStrukturbiochemie$$x0
001043478 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x1
001043478 9801_ $$aFullTexts
001043478 980__ $$ajournal
001043478 980__ $$aVDB
001043478 980__ $$aUNRESTRICTED
001043478 980__ $$aI:(DE-Juel1)IBI-7-20200312
001043478 980__ $$aI:(DE-Juel1)INM-3-20090406
001043478 980__ $$aAPC