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@ARTICLE{Mller:1043724,
author = {Møller, Marie Sofie and Bleckert, Anton and Jäckering,
Anna and Strodel, Birgit},
title = {{U}nraveling the relationship between {PET} surfaces and
their hydrolases},
journal = {Trends in biochemical sciences},
volume = {50},
number = {8},
issn = {0376-5067},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2025-03010},
pages = {707-},
year = {2025},
abstract = {Plastics, especially polyethylene terephthalate (PET), are
vital in modern life, with global production exceeding 400
million tons annually. This extensive use has led to
significant plastic waste pollution, highlighting the need
for effective recycling strategies. PET, one of the most
recycled plastics, is a prime candidate for degradation into
its original monomers through engineered PET hydrolases –
enzymes with industrial potential. While previous
engineering efforts have mainly focused on enhancing
thermostability and catalytic efficiency, the crucial aspect
of enzyme adsorption to PET surfaces has received less
attention. This review specifically addresses the mechanisms
of enzyme adsorption, detailing relevant experimental
methods and simulation techniques while emphasizing the
potential for engineering more effective PET hydrolases.},
cin = {IBI-7},
ddc = {540},
cid = {I:(DE-Juel1)IBI-7-20200312},
pnm = {5241 - Molecular Information Processing in Cellular Systems
(POF4-524)},
pid = {G:(DE-HGF)POF4-5241},
typ = {PUB:(DE-HGF)16},
pubmed = {40484801},
UT = {WOS:001587089400005},
doi = {10.1016/j.tibs.2025.05.002},
url = {https://juser.fz-juelich.de/record/1043724},
}