Journal Article FZJ-2025-03010

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Unraveling the relationship between PET surfaces and their hydrolases

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2025
Elsevier Science Amsterdam [u.a.]

Trends in biochemical sciences 50(8), 707- () [10.1016/j.tibs.2025.05.002]

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Abstract: Plastics, especially polyethylene terephthalate (PET), are vital in modern life, with global production exceeding 400 million tons annually. This extensive use has led to significant plastic waste pollution, highlighting the need for effective recycling strategies. PET, one of the most recycled plastics, is a prime candidate for degradation into its original monomers through engineered PET hydrolases – enzymes with industrial potential. While previous engineering efforts have mainly focused on enhancing thermostability and catalytic efficiency, the crucial aspect of enzyme adsorption to PET surfaces has received less attention. This review specifically addresses the mechanisms of enzyme adsorption, detailing relevant experimental methods and simulation techniques while emphasizing the potential for engineering more effective PET hydrolases.

Classification:

Contributing Institute(s):
  1. Strukturbiochemie (IBI-7)
Research Program(s):
  1. 5241 - Molecular Information Processing in Cellular Systems (POF4-524) (POF4-524)

Appears in the scientific report 2025
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Medline ; Creative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0 ; OpenAccess ; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 10 ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2025-07-08, last modified 2025-09-17


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