TY - JOUR AU - Bikulov, Timur AU - Abbas, Mohamad-Bilal AU - Krause, Hans-Joachim AU - Offenhäusser, Andreas AU - Engelmann, Ulrich TI - Dual-frequency MPS enables direct MNP size reconstruction: Verification with micromagnetic simulation dataInternational Journal on Magnetic Particle Imaging IJMPI JO - International journal on magnetic particle imaging VL - 11 IS - 1 SN - 2365-9033 CY - Lübeck PB - Infinite Science Publishing M1 - FZJ-2025-03863 SP - 2503005 PY - 2025 AB - Magnetic Particle Spectroscopy (MPS) allows for direct characterization of magneto-physical properties of magnetic nanoparticles (MNP), which are widely researched as imaging tracers, biosensing units and therapeutic heating agents. All these applications rely primarily on the core size-dependent magnetic particle relaxation dynamics. Therefore, knowledge about core size of any MNP sample is crucial. Dual-frequency MPS increases the characterization potential by considering frequency mixing terms of the received signal of MNP, from which their sizes can be approximated. In this work, preliminary feasibility and interpretation of a proposed size reconstruction method is tested against precisely simulated input data from stochastically coupled Néel-Brownian relaxation modeling using Monte Carlo implementation. T2 - International Workshop on Magnetic Particle Imaging CY - 17 Mar 2025 - 19 Mar 2025, Lübeck (Germany) Y2 - 17 Mar 2025 - 19 Mar 2025 M2 - Lübeck, Germany KW - dual-frequency (Other) KW - magnetic moment distribution (Other) KW - Monte-Carlo (Other) KW - nonlinear magnetization (Other) LB - PUB:(DE-HGF)8 ; PUB:(DE-HGF)16 DO - DOI:10.18416/IJMPI.2025.2503005 UR - https://juser.fz-juelich.de/record/1046553 ER -