Contribution to a conference proceedings/Journal Article

FZJ-2025-03863

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dual-frequency MPS enables direct MNP size reconstruction: Verification with micromagnetic simulation dataInternational Journal on Magnetic Particle Imaging IJMPI

Bikulov, T. (Corresponding author)FZJ* ; Abbas, M.-B. ; Krause, H.-J.FZJ* ; Offenhäusser, A.FZJ* ; Engelmann, U.

2025
Infinite Science Publishing Lübeck

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Please use a persistent id in citations: doi:10.18416/IJMPI.2025.2503005

Abstract: Magnetic Particle Spectroscopy (MPS) allows for direct characterization of magneto-physical properties of magnetic nanoparticles (MNP), which are widely researched as imaging tracers, biosensing units and therapeutic heating agents. All these applications rely primarily on the core size-dependent magnetic particle relaxation dynamics. Therefore, knowledge about core size of any MNP sample is crucial. Dual-frequency MPS increases the characterization potential by considering frequency mixing terms of the received signal of MNP, from which their sizes can be approximated. In this work, preliminary feasibility and interpretation of a proposed size reconstruction method is tested against precisely simulated input data from stochastically coupled Néel-Brownian relaxation modeling using Monte Carlo implementation.

Keyword(s): dual-frequency ; magnetic moment distribution ; Monte-Carlo ; nonlinear magnetization

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Contributing Institute(s):

1. Bioelektronik (IBI-3)

Research Program(s):

1. 5241 - Molecular Information Processing in Cellular Systems (POF4-524) (POF4-524)

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Database coverage:
; SCOPUS

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