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@ARTICLE{Dahmen:1050720,
author = {Dahmen, David and Hutt, Axel and Indiveri, Giacomo and
Kennedy, Ann and Lefebvre, Jeremie and Mazzucato, Luca and
Motter, Adilson E. and Narayanan, Rishikesh and Payvand,
Melika and Planert, Henrike and Gast, Richard},
title = {{H}ow heterogeneity shapes dynamics and computation in the
brain},
journal = {Neuron},
volume = {-},
number = {-},
issn = {0896-6273},
address = {[Cambridge, Mass.]},
publisher = {Cell Press},
reportid = {FZJ-2026-00465},
pages = {-},
year = {2025},
abstract = {Much effort has been spent clustering neurons into
transcriptomic or functional cell types and
characterizingthe differences between them. Beyond
subdividing neurons into categories, we must recognize that
no twoneurons are identical and that graded physiological or
transcriptomic properties exist within cells of agiven type.
This often overlooked ‘‘within-type’’ heterogeneity
is a specific neuronal implementation ofwhat statistical
physics refers to as ‘‘disorder’’ and exhibits rich
computational properties, the identificationof which may
shed crucial insights into theories of brain function. In
this perspective article, we address thisgap by highlighting
theoretical frameworks for the study of neural tissue
heterogeneity and discussing thebenefits and implications of
within-type heterogeneity for neural network dynamics,
computation, andself-organization.},
cin = {IAS-6},
ddc = {610},
cid = {I:(DE-Juel1)IAS-6-20130828},
pnm = {5231 - Neuroscientific Foundations (POF4-523) / 5232 -
Computational Principles (POF4-523) / DFG project
G:(GEPRIS)430157073 - Evolutinäre Konvergenz hierarchischer
Informationsverarbeitung (430157073)},
pid = {G:(DE-HGF)POF4-5231 / G:(DE-HGF)POF4-5232 /
G:(GEPRIS)430157073},
typ = {PUB:(DE-HGF)16},
doi = {10.1016/j.neuron.2025.11.023},
url = {https://juser.fz-juelich.de/record/1050720},
}