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@ARTICLE{Prott:1052780,
      author       = {Prott, Lea S. and Harlaß, Monique and Marksteiner,
                      Alexander and Spitznagel, Frank A. and Langner, Robert and
                      Zhang, Yu and Blatz, Markus B. and Gierthmuehlen, Petra C.},
      title        = {{F}atigue performance and failure load of
                      minimally-invasive occlusal veneers made of lithium
                      disilicate and composition-gradient multilayered zirconia:
                      {A}n in vitro study},
      journal      = {Journal of prosthodontic research},
      volume       = {-},
      issn         = {1883-1958},
      address      = {Amstedam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {FZJ-2026-01137},
      pages        = {$JPR_D_25_00068$},
      year         = {2025},
      abstract     = {Purpose: To investigate the effect of ceramic material
                      (lithium disilicate, LDS vs. composition-gradient
                      multilayered zirco-nia [4Y-PSZ and 5-PSZ], Z) and ceramic
                      layer thickness (0.5 mm, 1.0 mm, and 1.5 mm) on fatigue
                      performance and failureload of occlusal veneers on
                      molars.Methods: Seventy-two CAD-CAM-fabricated occlusal
                      veneer restorations (IPS e.max CAD; IPS e.max ZirCAD Prime
                      Es-thetic, Ivoclar Vivadent) were divided into six groups
                      (n=12, LDS-1.5, LDS-1.0, LDS-0.5; Z-1.5, Z-1.0, Z-0.5).
                      Restorations wereadhesively cemented (Variolink Esthetic DC,
                      Ivoclar Vivadent) to dentin-analogue composite dies (Z100,
                      3M ESPE) andexposed to thermomechanical fatigue (1.2 million
                      cycles, 49 N, 1.6 Hz, 5-55° C). Single-load-to-failure was
                      tested with auniversal testing machine. Data were analyzed
                      using ANOVA with Tukey post-hoc tests and t-tests (P <
                      0.05).Results: The overall success rate across all materials
                      and layer thicknesses was $91.7\%.$ Half of the specimens of
                      group Z-0.5revealed cracks after chewing simulation.
                      Occlusal veneers fabricated from LDS withstood significantly
                      higher failure loadsthan gradient multilayered zirconia
                      veneers in all tested thicknesses. The mean failure load
                      values led to the followingranking: 3194 N (LDS-0.5)>2683 N
                      (LDS-1.0)>2338 N (LDS-1.5)>1744 N (Z-1.5)>1310 N
                      (Z-0.5)>1198 N (Z-1.0).Conclusions: Ultrathin LDS occlusal
                      veneers outperformed thin and standard thick counterparts,
                      as well as gradientmultilayered zirconia veneers at all
                      thickness levels. Ultrathin gradient multilayered zirconia
                      occlusal veneers were proneto cracks during thermomechanical
                      fatigue. Individual mechanical properties need to be
                      considered when aligning therestoration within the
                      multilayered zirconia blank.Keywords: Ceramics, Occlusal
                      veneer, Ceramic thickness, Fatigue, Computer-aided design},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.2186/jpr.JPR_D_25_00068},
      url          = {https://juser.fz-juelich.de/record/1052780},
}