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000010808 0247_ $$2pmid$$apmid:17712097
000010808 0247_ $$2DOI$$a10.1007/s10967-010-0460-5
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000010808 041__ $$aeng
000010808 082__ $$a540
000010808 084__ $$2WoS$$aChemistry, Analytical
000010808 084__ $$2WoS$$aChemistry, Inorganic & Nuclear
000010808 084__ $$2WoS$$aNuclear Science & Technology
000010808 1001_ $$0P:(DE-Juel1)VDB1300$$aQaim, S. M.$$b0$$uFZJ
000010808 245__ $$aRadiochemical determination of nuclear data for therapy and applications
000010808 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V$$c2010
000010808 300__ $$a489 - 505
000010808 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000010808 3367_ $$2BibTeX$$aARTICLE
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000010808 3367_ $$2DRIVER$$aarticle
000010808 440_0 $$03752$$aJournal of Radioanalytical and Nuclear Chemistry$$v284$$x0236-5731$$y3
000010808 500__ $$aThe article gives a brief review of the work carried out over a period of more than 35 years at the Institute of Nuclear Chemistry of the Research Centre Julich, Germany. I am highly indebted to Professor Dr. G. Stocklin and Prof. Dr. H. H. Coenen, the former and present directors of the Institute, for their continuous support of this field of study, and to my own research group for painstaking efforts in acquisition and analysis of data. A large number of Ph.D. students and guest scientists also contributed appreciably to our efforts. My special thanks are due to about 10 Hungarian scientists for a long-term and fruitful cooperation both in experimental studies and nuclear model calculations. The partial financial supports of some external funding agencies like DFG, DAAD, EU, IAEA, etc. are gratefully acknowledged.
000010808 520__ $$aTo examine the association between presence of clinically relevant depressive symptoms (Center for Epidemiologic Studies Depression Scale [CES-D] score >or= 16) and subsequent cognitive function (Mini-Mental State Examination [MMSE]) over a 7-year period in older Mexican Americans, a prospective cohort study was performed. Five south-western states contributed data to the Hispanic Established Populations for Epidemiologic Studies of the Elderly. Participants included 2812 noninstitutionalized Mexican Americans aged 65 and older followed from 1993-1994 until 2000-2001. Cognitive change was assessed using the MMSE at baseline and at 2, 5, and 7 years of follow-up. Independent variables were sociodemographics, CES-D >or= 16, medical conditions (hypertension, diabetes, coronary artery disease, and stroke), and activities of daily living (ADL) status. A general linear mixed model was used to estimate cognitive change. There was a cross-sectional association between CES-D >or= 16 and lower MMSE score (estimate = -0.48; standard error [SE] = 0.15; P < .01), independent of age, gender, education, marital status, time of interview, ADL limitations, vision impairment, and medical conditions. In the fully adjusted longitudinal model, subjects with clinically relevant depressive symptoms had a greater decline in MMSE score over 7 years than those without clinically relevant depressive symptoms (estimate = -0.17; SE = 0.05; P < .001), adjusting for sociodemographics, ADL and medical conditions. Each point increase in the CES-D score was associated with a decline of 0.010 point in MMSE score per year (SE = 0.002; P < 0.0001), adjusting for relevant confounders. Presence of clinically relevant depressive symptoms was associated with subsequent decline in cognitive function over 7 years in older Mexican Americans, independent of demographic and health factors.
000010808 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
000010808 536__ $$0G:(DE-HGF)POF2-89573$$a89573 - Neuroimaging (POF2-89573)$$cPOF2-89573$$fPOF II T$$x1
000010808 588__ $$aDataset connected to Web of Science, Pubmed
000010808 650_2 $$2MeSH$$aActivities of Daily Living
000010808 650_2 $$2MeSH$$aAged
000010808 650_2 $$2MeSH$$aAging: psychology
000010808 650_2 $$2MeSH$$aCognition
000010808 650_2 $$2MeSH$$aCognition Disorders: diagnosis
000010808 650_2 $$2MeSH$$aCognition Disorders: epidemiology
000010808 650_2 $$2MeSH$$aCognition Disorders: psychology
000010808 650_2 $$2MeSH$$aCohort Studies
000010808 650_2 $$2MeSH$$aDepressive Disorder: diagnosis
000010808 650_2 $$2MeSH$$aDepressive Disorder: epidemiology
000010808 650_2 $$2MeSH$$aDepressive Disorder: psychology
000010808 650_2 $$2MeSH$$aFemale
000010808 650_2 $$2MeSH$$aFollow-Up Studies
000010808 650_2 $$2MeSH$$aGeriatric Assessment: methods
000010808 650_2 $$2MeSH$$aGeriatric Assessment: statistics & numerical data
000010808 650_2 $$2MeSH$$aHealth Status
000010808 650_2 $$2MeSH$$aHumans
000010808 650_2 $$2MeSH$$aMale
000010808 650_2 $$2MeSH$$aMexican Americans: psychology
000010808 650_2 $$2MeSH$$aMexican Americans: statistics & numerical data
000010808 650_2 $$2MeSH$$aProspective Studies
000010808 650_2 $$2MeSH$$aPsychiatric Status Rating Scales: statistics & numerical data
000010808 650_2 $$2MeSH$$aSocioeconomic Factors
000010808 650_7 $$2WoSType$$aJ
000010808 65320 $$2Author$$aNuclear reactions
000010808 65320 $$2Author$$aNuclear data
000010808 65320 $$2Author$$aRadiochemical methods
000010808 65320 $$2Author$$aComplex particle emission
000010808 65320 $$2Author$$aIsomeric cross section
000010808 65320 $$2Author$$aFusion reactor technology
000010808 65320 $$2Author$$aMedical radionuclide production
000010808 773__ $$0PERI:(DE-600)2017242-4$$a10.1007/s10967-010-0460-5$$gVol. 284, p. 489 - 505$$p489 - 505$$q284<489 - 505$$tJournal of radioanalytical and nuclear chemistry$$v284$$x0236-5731$$y2010
000010808 8567_ $$uhttp://dx.doi.org/10.1007/s10967-010-0460-5
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000010808 9132_ $$0G:(DE-HGF)POF3-573$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vNeuroimaging$$x0
000010808 9131_ $$0G:(DE-HGF)POF2-89573$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vNeuroimaging$$x1
000010808 9141_ $$y2010
000010808 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000010808 9201_ $$0I:(DE-Juel1)INM-5-20090406$$gINM$$kINM-5$$lNuklearchemie$$x0
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