TY  - JOUR
AU  - Reshetnyak, A.B.
AU  - Borshchevskii, V.I.
AU  - Klare, J.
AU  - Moiseeva, E.S.
AU  - Engelhardt, M.
AU  - Büldt, G.
AU  - Gordeliy, V. I.
TI  - Comparative Analysis of Sensory Rhodopsin II Structures in Complex with a Transducer and without It
JO  - Journal of Surface Investigation. X-ray, Synchrotron and Neutron Techniques
VL  - 2
SN  - 1027-4510
CY  - Moscow
PB  - MAIK Nauka/Interperiodics Publ.
M1  - PreJuSER-1104
SP  - 894 - 899
PY  - 2008
N1  - Record converted from VDB: 12.11.2012
AB  - Sensory rhodopsin II (NpSRII) is a heptahelical transmembrane protein containing the retinal chromophore. In complex with another membrane protein, i.e., NpHtrII transducer, NpSRII transmits a signal into a cell, initiating negative phototaxis of Natronobacterium pharaonis. In the absence of a transducer, rhodopsin II can work as a proton pump similar to bacteriorhodopsin. The main objective of this study is to comparatively analyze receptor structures in complex with the transducer and without it to understand the mechanism of the protein switching function. Diffraction data for sensory rhodopsin II crystals grown in the lipidic cubic phase were obtained at the synchrotron x-ray source. In this paper, we present a new NpSRII structure with a resolution of 2.1 angstrom and the results of a comparative analysis of the obtained NpSRII structure with our previously published data on the NpSRII/NpHtrII complex structure and with two NpSRII structures without a transducer, previously published in the literature.
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000262864900012
DO  - DOI:10.1134/S1027451008060128
UR  - https://juser.fz-juelich.de/record/1104
ER  -