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000012994 005__ 20180208224706.0
000012994 0247_ $$2pmid$$apmid:7857705
000012994 0247_ $$2DOI$$a10.1007/s11099-010-0079-3
000012994 0247_ $$2WOS$$aWOS:000286115100016
000012994 037__ $$aPreJuSER-12994
000012994 041__ $$aeng
000012994 082__ $$a570
000012994 084__ $$2WoS$$aPlant Sciences
000012994 1001_ $$0P:(DE-HGF)0$$aKutschera, U.$$b0
000012994 245__ $$aLeaf development, gas exchange characteristics, and photorespiratory activity in maize seedlings
000012994 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V$$c2010
000012994 300__ $$a617 - 622
000012994 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000012994 3367_ $$2BibTeX$$aARTICLE
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000012994 3367_ $$2DRIVER$$aarticle
000012994 440_0 $$023382$$aPhotosynthetica$$v48$$x0300-3604$$y4
000012994 500__ $$aThis work was supported by grants from the Alexander von Humboldt Foundation (AvH-fellowships 2007/2008, Stanford/USA to U. K.). R. P. (Present address: ICG-3: Phytosphere Forschungszentrum Julich, 52425 Julich, Germany) was supported by the Marie Curie International Outgoing Fellowship Program (Nr: 041060 - LIFT).
000012994 520__ $$aApoptotic cells were quantitated by light microscopy in a series of 288 breast carcinomas, and their number (cells/mm2 of neoplastic epithelium, i.e., the apoptotic index, AI) was related to various histopathological features and disease outcome. High AI was associated with tumour necrosis (P = 0.003), lack of tubule formation (P = 0.03), dense stromal lymphocyte infiltration (P = 0.0009), high grade of the tumour (P < 0.0001), DNA aneuploidy (P = 0.049), high S-phase fraction (P = 0.010), high mitotic rate (P < 0.0001), lack of sex steroid receptors (P = 0.004), expression of p53 tumour suppressor gene (P = 0.004), and high values of morphometrically measured nuclear factors (P < 0.05). In survival analysis, an AI greater than 3/mm2 was related to short recurrence-free survival in the entire cohort (P = 0.0079) as well as in the axillary lymph node-negative tumours (P = 0.0253). Survival of the patients with node-negative tumours (P = 0.0356), node-positive tumours (P = 0.0085) and in the entire cohort (P = 0.004) was related to AI. Recurrence-free survival was related to the mitotic index (P = 0.0012), ductal type (P = 0.011), S.D. of the nuclear area (P = 0.075), and axillary lymph node status (P = 0.096). Cox's analysis showed that only the tumour diameter (P < 0.001), axillary lymph node status (P = 0.001), progesterone receptor content (P = 0.004) and ductal type (P = 0.041) had independent prognostic value, whereas AI did not.
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000012994 65320 $$2Author$$aleaf development
000012994 65320 $$2Author$$amaize seedlings
000012994 65320 $$2Author$$aphotorespiration
000012994 65320 $$2Author$$aphotosynthesis
000012994 650_2 $$2MeSH$$aAdult
000012994 650_2 $$2MeSH$$aAged
000012994 650_2 $$2MeSH$$aAged, 80 and over
000012994 650_2 $$2MeSH$$aApoptosis
000012994 650_2 $$2MeSH$$aBreast Neoplasms: chemistry
000012994 650_2 $$2MeSH$$aBreast Neoplasms: mortality
000012994 650_2 $$2MeSH$$aBreast Neoplasms: pathology
000012994 650_2 $$2MeSH$$aCarcinoma, Ductal, Breast: pathology
000012994 650_2 $$2MeSH$$aFemale
000012994 650_2 $$2MeSH$$aFlow Cytometry
000012994 650_2 $$2MeSH$$aHumans
000012994 650_2 $$2MeSH$$aLymphatic Metastasis
000012994 650_2 $$2MeSH$$aMiddle Aged
000012994 650_2 $$2MeSH$$aMitotic Index
000012994 650_2 $$2MeSH$$aPrognosis
000012994 650_2 $$2MeSH$$aReceptors, Progesterone: analysis
000012994 650_2 $$2MeSH$$aSurvival Rate
000012994 650_7 $$00$$2NLM Chemicals$$aReceptors, Progesterone
000012994 650_7 $$2WoSType$$aJ
000012994 7001_ $$0P:(DE-Juel1)129379$$aPieruschka, R.$$b1$$uFZJ
000012994 7001_ $$0P:(DE-HGF)0$$aBerry, J.A.$$b2
000012994 773__ $$0PERI:(DE-600)2018590-X$$a10.1007/s11099-010-0079-3$$gVol. 48, p. 617 - 622$$p617 - 622$$q48<617 - 622$$tPhotosynthetica$$v48$$x0300-3604$$y2010
000012994 8567_ $$uhttp://dx.doi.org/10.1007/s11099-010-0079-3
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