001     12994
005     20180208224706.0
024 7 _ |2 pmid
|a pmid:7857705
024 7 _ |2 DOI
|a 10.1007/s11099-010-0079-3
024 7 _ |2 WOS
|a WOS:000286115100016
037 _ _ |a PreJuSER-12994
041 _ _ |a eng
082 _ _ |a 570
084 _ _ |2 WoS
|a Plant Sciences
100 1 _ |0 P:(DE-HGF)0
|a Kutschera, U.
|b 0
245 _ _ |a Leaf development, gas exchange characteristics, and photorespiratory activity in maize seedlings
260 _ _ |a Dordrecht [u.a.]
|b Springer Science + Business Media B.V
|c 2010
300 _ _ |a 617 - 622
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |0 23382
|a Photosynthetica
|v 48
|x 0300-3604
|y 4
500 _ _ |a This work was supported by grants from the Alexander von Humboldt Foundation (AvH-fellowships 2007/2008, Stanford/USA to U. K.). R. P. (Present address: ICG-3: Phytosphere Forschungszentrum Julich, 52425 Julich, Germany) was supported by the Marie Curie International Outgoing Fellowship Program (Nr: 041060 - LIFT).
520 _ _ |a Apoptotic cells were quantitated by light microscopy in a series of 288 breast carcinomas, and their number (cells/mm2 of neoplastic epithelium, i.e., the apoptotic index, AI) was related to various histopathological features and disease outcome. High AI was associated with tumour necrosis (P = 0.003), lack of tubule formation (P = 0.03), dense stromal lymphocyte infiltration (P = 0.0009), high grade of the tumour (P < 0.0001), DNA aneuploidy (P = 0.049), high S-phase fraction (P = 0.010), high mitotic rate (P < 0.0001), lack of sex steroid receptors (P = 0.004), expression of p53 tumour suppressor gene (P = 0.004), and high values of morphometrically measured nuclear factors (P < 0.05). In survival analysis, an AI greater than 3/mm2 was related to short recurrence-free survival in the entire cohort (P = 0.0079) as well as in the axillary lymph node-negative tumours (P = 0.0253). Survival of the patients with node-negative tumours (P = 0.0356), node-positive tumours (P = 0.0085) and in the entire cohort (P = 0.004) was related to AI. Recurrence-free survival was related to the mitotic index (P = 0.0012), ductal type (P = 0.011), S.D. of the nuclear area (P = 0.075), and axillary lymph node status (P = 0.096). Cox's analysis showed that only the tumour diameter (P < 0.001), axillary lymph node status (P = 0.001), progesterone receptor content (P = 0.004) and ductal type (P = 0.041) had independent prognostic value, whereas AI did not.
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588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Adult
650 _ 2 |2 MeSH
|a Aged
650 _ 2 |2 MeSH
|a Aged, 80 and over
650 _ 2 |2 MeSH
|a Apoptosis
650 _ 2 |2 MeSH
|a Breast Neoplasms: chemistry
650 _ 2 |2 MeSH
|a Breast Neoplasms: mortality
650 _ 2 |2 MeSH
|a Breast Neoplasms: pathology
650 _ 2 |2 MeSH
|a Carcinoma, Ductal, Breast: pathology
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Flow Cytometry
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Lymphatic Metastasis
650 _ 2 |2 MeSH
|a Middle Aged
650 _ 2 |2 MeSH
|a Mitotic Index
650 _ 2 |2 MeSH
|a Prognosis
650 _ 2 |2 MeSH
|a Receptors, Progesterone: analysis
650 _ 2 |2 MeSH
|a Survival Rate
650 _ 7 |0 0
|2 NLM Chemicals
|a Receptors, Progesterone
650 _ 7 |2 WoSType
|a J
653 2 0 |2 Author
|a leaf development
653 2 0 |2 Author
|a maize seedlings
653 2 0 |2 Author
|a photorespiration
653 2 0 |2 Author
|a photosynthesis
700 1 _ |0 P:(DE-Juel1)129379
|a Pieruschka, R.
|b 1
|u FZJ
700 1 _ |0 P:(DE-HGF)0
|a Berry, J.A.
|b 2
773 _ _ |0 PERI:(DE-600)2018590-X
|a 10.1007/s11099-010-0079-3
|g Vol. 48, p. 617 - 622
|p 617 - 622
|q 48<617 - 622
|t Photosynthetica
|v 48
|x 0300-3604
|y 2010
856 7 _ |u http://dx.doi.org/10.1007/s11099-010-0079-3
909 C O |o oai:juser.fz-juelich.de:12994
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