Journal Article PreJuSER-14895

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Three Brain Collections for Comparative Neuroanatomy and Neuroimaging

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2011
Wiley-Blackwell Oxford [u.a.]

Annals of the New York Academy of Sciences 1225, E94 - E104 () [10.1111/j.1749-6632.2011.05978.x]

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Abstract: In the context of increasing extinction rates and the potential loss of essential evolutionary biological and anthropological information, it is an important task to support efforts to prepare, preserve, and curate collections of histological brain sections; to disseminate information on such collections in the neuroscience community; and to make the collections publicly available. This review emphasizes the importance of complete, serially sectioned human brains of different ontogenetic stages as well as those of adult and old human individuals for neurobiological and medical research. Such histological sections enable microstructural analyses and anatomical evaluations of functional and structural neuroimaging data, for example, based on magnetic resonance imaging. Here, this review provides the first detailed and updated account of the content of the Stephan, Zilles, and Zilles-Amunts collections, which consist of serially sectioned and cell body- and myelin-stained histological preparations. Finally, this review will give an overview of past and recent research using these collections to increase our understanding of the detailed patterns of divergent brain evolution in primates as well as of the structural organization of the human brain.

Keyword(s): Adult (MeSH) ; Aged (MeSH) ; Aging (MeSH) ; Anatomy, Comparative: methods (MeSH) ; Anatomy, Cross-Sectional (MeSH) ; Animals (MeSH) ; Biological Specimen Banks: organization & administration (MeSH) ; Brain: anatomy & histology (MeSH) ; Brain: cytology (MeSH) ; Brain: embryology (MeSH) ; Brain: growth & development (MeSH) ; Child (MeSH) ; Fetus: anatomy & histology (MeSH) ; Fetus: cytology (MeSH) ; Humans (MeSH) ; Infant (MeSH) ; Neuroanatomy: methods (MeSH) ; Primates (MeSH) ; S ; brain collections (auto) ; comparative neuroanatomy (auto) ; neuroimaging (auto) ; brain mapping (auto) ; cytoarchitectonics (auto)

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Note: This work was supported by the EC FP6 HANDTO-MOUTH project (Contract No. 29065).

Contributing Institute(s):
  1. Molekulare Organisation des Gehirns (INM-2)
  2. Strukturelle und funktionelle Organisation des Gehirns (INM-1)
Research Program(s):
  1. Funktion und Dysfunktion des Nervensystems (FUEK409) (FUEK409)
  2. 89574 - Theory, modelling and simulation (POF2-89574) (POF2-89574)

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 Record created 2012-11-13, last modified 2021-01-29



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