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@INPROCEEDINGS{Wu:150589,
author = {Wu, C. and Poghossian, A. and Werner, C. F. and Bronder, T.
and Bäcker, M. and Schöning, M. J. and Wang, P.},
title = {{A}n application of a scanning light-addressable
potentiometric sensor for label-free {DNA} detection},
publisher = {AMA Service GmbH, P.O. Box 2352, 31506 Wunstorf, Germany},
reportid = {FZJ-2014-00638},
pages = {164-168},
year = {2013},
abstract = {In this study, a scanning light-addressable potentiometric
sensor (LAPS) was applied for label-free and direct
electrical detection of DNA (deoxyribonucleic acid)
hybridization for the first time. The functioning principle
of the sensor is based on an electrostatic detection of the
intrinsic molecular charge of DNA molecules together with an
ion-concentration redistribution within intermolecular
spaces. The LAPS signal shows a distinct dependence on the
concentration of the complementary target DNA. The mechanism
of the shift of the photocurrent-voltage curve and the LAPS
signal generation induced by the DNA immobilization and
hybridization event is discussed.},
month = {Dec},
date = {2013-12-09},
organization = {11. Dresdner Sensor-Symposium, Dresden
(Germany), 9 Dec 2013 - 11 Dec 2013},
cin = {PGI-8 / JARA-FIT / ICS-8},
cid = {I:(DE-Juel1)PGI-8-20110106 / $I:(DE-82)080009_20140620$ /
I:(DE-Juel1)ICS-8-20110106},
pnm = {423 - Sensorics and bioinspired systems (POF2-423) / 453 -
Physics of the Cell (POF2-453)},
pid = {G:(DE-HGF)POF2-423 / G:(DE-HGF)POF2-453},
typ = {PUB:(DE-HGF)8},
doi = {10.5162/11dss2013/A9},
url = {https://juser.fz-juelich.de/record/150589},
}