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@ARTICLE{Fedosov:153935,
author = {Fedosov, Dmitry A. and Peltomäki, Matti and Gompper,
Gerhard},
title = {{D}eformation and dynamics of red blood cells in flow
through cylindrical microchannels},
journal = {Soft matter},
volume = {10},
number = {24},
issn = {1744-6848},
address = {Cambridge},
publisher = {Royal Society of Chemistry (RSC)},
reportid = {FZJ-2014-03388},
pages = {4258 - 4267},
year = {2014},
abstract = {The motion of red blood cells (RBCs) in microcirculation
plays an important role in blood flow resistance and in the
cell partitioning within a microvascular network. Different
shapes and dynamics of RBCs in microvessels have been
previously observed experimentally including the parachute
and slipper shapes. We employ mesoscale hydrodynamic
simulations to predict the phase diagram of shapes and
dynamics of RBCs in cylindrical microchannels, which serve
as idealized microvessels, for a wide range of channel
confinements and flow rates. A rich dynamical behavior is
found, with snaking and tumbling discocytes, slippers
performing a swinging motion, and stationary parachutes. We
discuss the effects of different RBC states on the flow
resistance, and the influence of RBC properties,
characterized by the Föppl–von Kármán number, on the
shape diagram. The simulations are performed using the same
viscosity for both external and internal fluids surrounding
a RBC; however, we discuss how the viscosity contrast would
affect the shape diagram},
cin = {IAS-2 / ICS-2},
ddc = {530},
cid = {I:(DE-Juel1)IAS-2-20090406 / I:(DE-Juel1)ICS-2-20110106},
pnm = {451 - Soft Matter Composites (POF2-451)},
pid = {G:(DE-HGF)POF2-451},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000337112600005},
doi = {10.1039/c4sm00248b},
url = {https://juser.fz-juelich.de/record/153935},
}