% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Hoffmann:154440,
      author       = {Hoffmann, Ingo and Michel, Raphael and Sharp, Melissa and
                      Holderer, Olaf and Appavou, Marie-Sousai and Polzer, Frank
                      and Farago, Bela and Gradzielski, Michael},
      title        = {{S}oftening of phospholipid membranes by the adhesion of
                      silica nanoparticles – as seen by neutron spin-echo
                      ({NSE})},
      journal      = {Nanoscale},
      volume       = {6},
      number       = {12},
      issn         = {2040-3372},
      address      = {Cambridge},
      publisher    = {RSC Publ.},
      reportid     = {FZJ-2014-03787},
      pages        = {6945 - 6952},
      year         = {2014},
      abstract     = {The interactions between nanoparticles and vesicles are of
                      significant interest both from a fundamental as well as from
                      a practical point of view, as vesicles can serve as a model
                      system for cell membranes. Accordingly the effect of
                      nanoparticles that bind to the vesicle bilayer is very
                      important with respect to understanding their biological
                      impact and also may shed some light on the mechanisms behind
                      the effect of nanotoxicity. In this study we have
                      investigated the influence of small adsorbed silica
                      nanoparticles (SiNPs) on the structure of zwitterionic DOPC
                      vesicles. By a combination of SANS, cryo-TEM, and DLS, we
                      observed that the SiNPs are bound to the outer vesicle
                      surface without significantly affecting the vesicle
                      structure. Most interestingly, by means of neutron spin-echo
                      (NSE) local bilayer fluctuations were studied and one finds
                      a small but marked decrease of the membrane rigidity upon
                      binding of the nanoparticles. This surprising finding may be
                      a relevant aspect for the further understanding of the
                      effects that nanoparticles have on phospholipid bilayers},
      cin          = {Neutronenstreuung ; JCNS-1 / JCNS (München) ; Jülich
                      Centre for Neutron Science JCNS (München) ; JCNS-FRM-II /
                      ICS-1},
      ddc          = {600},
      cid          = {I:(DE-Juel1)JCNS-1-20110106 /
                      I:(DE-Juel1)JCNS-FRM-II-20110218 /
                      I:(DE-Juel1)ICS-1-20110106},
      pnm          = {451 - Soft Matter Composites (POF2-451) / 54G - JCNS
                      (POF2-54G24)},
      pid          = {G:(DE-HGF)POF2-451 / G:(DE-HGF)POF2-54G24},
      experiment   = {EXP:(DE-MLZ)J-NSE-20140101 / EXP:(DE-MLZ)KWS2-20140101},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000337143900087},
      doi          = {10.1039/c4nr00774c},
      url          = {https://juser.fz-juelich.de/record/154440},
}