Journal Article

PreJuSER-15723

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Dissipation and sequestration of the veterinary antibiotic sulfadiazine and its metabolites under field conditions

Rosendahl, I. ; Siemens, J. ; Groeneweg, J.FZJ* ; Linzbach, E. ; Laabs, V. ; Herrmann, C. ; Vereecken, H.FZJ* ; Amelung, W.

2011
American Chemical Society Columbus, Ohio

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Please use a persistent id in citations: doi:10.1021/es200326t

Abstract: Veterinary antibiotics introduced into the environment may change the composition and functioning of soil microbial communities and promote the spreading of antibiotic resistance. Actual risks depend on the antibiotic's persistence and (bio)accessibility, which may differ between laboratory and field conditions. We examined the dissipation and sequestration of sulfadiazine (SDZ) and its main metabolites in soil under field conditions and how it was influenced by temperature, soil moisture, plant roots, and soil aggregation compared to controlled laboratory experiments. A sequential extraction accounted for easily extractable (CaCl₂-extractable) and sequestered (microwave-extractable, residual) SDZ fractions. Dissipation from both fractions was largely temperature-dependent and could be well predicted from laboratory data recorded at different temperatures. Soil moisture additionally seemed to control sequestration, being accelerated in dry soil. Sequestration, as indicated by increasing apparent distribution coefficients and decreasing rates of kinetic release into CaCl₂, governed the antibiotic's long-term fate in soil. Besides, we observed spatial gradients of antibiotic concentrations across soil aggregates and in the vicinity of roots. The former were short-lived and equilibrated due to aggregate reorganization, while dissipation of the easily extractable fraction was accelerated near roots throughout the growth period. There was little if any impact of the plants on residual SDZ concentrations.

Keyword(s): Anti-Bacterial Agents: isolation & purification (MeSH) ; Biodegradation, Environmental (MeSH) ; Environmental Monitoring (MeSH) ; Environmental Remediation: methods (MeSH) ; Rhizosphere (MeSH) ; Soil: chemistry (MeSH) ; Sulfadiazine: analogs & derivatives (MeSH) ; Sulfadiazine: isolation & purification (MeSH) ; Veterinary Drugs: analogs & derivatives (MeSH) ; Veterinary Drugs: isolation & purification (MeSH) ; Zea mays: metabolism (MeSH) ; Anti-Bacterial Agents ; Soil ; Veterinary Drugs ; Sulfadiazine ; J

Note: We thank Marisa Guttler for her great help in the lab, the team of the Frankenforst agricultural research station for providing their facilities for manure production, and Herbert Rutzel for supporting the field work. We furthermore thank Vetoquinol Biowet (Gorzow Wielkopolski, Poland) for preparing the SDZ injection solution, and our colleagues of the research unit FOR 566 for practical help during sampling campaigns and inspiring discussions of the results. This project was funded by the German Research Foundation (DFG) within the Research Unit FOR 566 "Veterinary medicines in soil: basic research for risk assessment" (AM 134/6-3).

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Contributing Institute(s):

1. Agrosphäre (IBG-3)

Research Program(s):

1. Terrestrische Umwelt (P24)

Appears in the scientific report 2011

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Database coverage:
; JCR ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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