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@ARTICLE{Kumtabtim:16488,
author = {Kumtabtim, U. and Matusch, A. and Dani, S.U. and
Siripinyanond, A. and Becker, J.S.},
title = {{B}iomonitoring for arsenic, toxic and essential metals in
single hair strands by laser ablation inductively coupled
plasma mass spectrometry},
journal = {International journal of mass spectrometry},
volume = {307},
issn = {1387-3806},
address = {[S.l.]},
publisher = {Elsevier Science},
reportid = {PreJuSER-16488},
pages = {185–191},
year = {2011},
note = {The authors would like to thank Thermo Scientific, Bremen
for instrumental support for the Brain Met Centre and L.
Terrier for providing hair samples. Usarat Kumtabtim would
like to acknowledge the Office of Higher Education
Commission (Thailand) for financial support of her research
in the Brain Met laboratory at Forschungszentrum Julich
(www.brainmet.com/).},
abstract = {Laser ablation inductively coupled plasma mass spectrometry
(LA-ICP-MS) has been developed as reliable analytical
technique for the quantitation of metal distributions at
micrometre resolution. In this work a novel microanalytical
strategy for biomonitoring of arsenic, toxic and essential
metals in single hair strands is proposed. Two different
calibration strategies in LA-ICP-MS were developed using
either certified hair standard reference material (IAEA 086)
or prepared matrix-matched laboratory hair standards doped
with analytes of interest at defined concentration. Powdered
hair standards and human hair strands mounted on a sticky
tape in the LA chamber were analyzed under the same
experimental conditions by an optimized LA-ICP-MS technique.
The use of hair powder standard allows calibration curves to
be obtained by plotting the analyte ion (M+) intensity
normalized to S-34(+) (the ratio M+/S-34(+)) as a function
of the concentration determined by ICP-MS of acidic digests.
The linear correlation coefficients (R) of calibration
curves for analytes As, Ba, Cd, Ce, Co, Cr, Cu, Fe, Ga, Hg,
Mg, Mo, Ni, Pb, Rb, Sr, Ti and U were typically between
0.985 and 0.999. The limit of detection (LOD) was 0.6 mu g
g(-1) for As and ranged from 0.3 to 7.8 mu g g(-1) for the
other analytes. Distinct elemental exposition time profiles
were observed in hair samples from five volunteers. (C) 2011
Elsevier B.V. All rights reserved.},
keywords = {J (WoSType)},
cin = {ZCH / INM-2},
ddc = {530},
cid = {I:(DE-Juel1)ZCH-20090406 / I:(DE-Juel1)INM-2-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89571 - Connectivity and Activity (POF2-89571)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
shelfmark = {Physics, Atomic, Molecular $\&$ Chemical / Spectroscopy},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000295864100026},
doi = {10.1016/j.ijms.2011.03.007},
url = {https://juser.fz-juelich.de/record/16488},
}