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@ARTICLE{Wendland:17016,
      author       = {Wendland, F. and Berthold, G. and Fritsche, J.-G. and
                      Herrmann, F. and Kunkel, R. and Voigt, H.-J. and Vereecken,
                      H.},
      title        = {{A} conceptual hydrogeological model for evaluating
                      residence times in {H}essen},
      journal      = {Grundwasser},
      volume       = {16},
      issn         = {1430-483X},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {PreJuSER-17016},
      pages        = {163 - 176},
      year         = {2011},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {The association between long-term use of
                      depot-medroxyprogesterone acetate (DMPA) and bone mineral
                      density (BMD) has been controversial, as seen in three
                      case-control studies in New Zealand, Thailand, and the
                      United Kingdom. In the present case-controlled study of BMD,
                      a group of 67 Chinese women who had used DMPA from 5-15
                      years was compared with 218 women of the same age range who
                      had not used any steroidal hormones. DMPA users were found
                      to have a significantly lower BMD at lumbar vertebra (L2-4)
                      (0.93 g/cm2), neck of femur (0.69 g/cm2), trochanter (0.59
                      g/cm2), and Ward's triangle (0.58 g/cm2), as compared with
                      the control group, whose corresponding BMD values were 1.03
                      g/cm2, 0.83 g/cm2, 0.71 g/cm2, and 0.78 g/cm2, respectively
                      (p < 0.001). The average percentage of bone loss per year
                      was estimated to be $1.1\%$ in L2-4, $2.3\%$ in neck of
                      femur, $2.4\%$ in trochanter, and $3.5\%$ in Ward's
                      triangle. The percentage of bone loss in L2-4 was found to
                      be more pronounced with age. This study provided information
                      that the use of DMPA in a Chinese group for > 5 years in
                      associated with bone loss, and a prospective study is needed
                      to confirm these data, which are different from two
                      case-control studies.},
      keywords     = {Absorptiometry, Photon / Adult / Age Factors / Amenorrhea /
                      Body Mass Index / Bone Density: drug effects / Bone
                      Resorption: etiology / Calcium: metabolism / Case-Control
                      Studies / China / Contraceptive Agents, Female: pharmacology
                      / Female / Femur: physiopathology / Humans / Lumbar
                      Vertebrae: physiopathology / Medroxyprogesterone Acetate:
                      pharmacology / Middle Aged / Questionnaires / Regression
                      Analysis / Contraceptive Agents, Female (NLM Chemicals) /
                      Medroxyprogesterone Acetate (NLM Chemicals) / Calcium (NLM
                      Chemicals) / J (WoSType)},
      cin          = {IBG-3},
      ddc          = {690},
      cid          = {I:(DE-Juel1)IBG-3-20101118},
      pnm          = {Terrestrische Umwelt},
      pid          = {G:(DE-Juel1)FUEK407},
      shelfmark    = {Environmental Sciences / Water Resources},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:10342083},
      UT           = {WOS:000294471600004},
      doi          = {10.1007/s00767-011-0169-6},
      url          = {https://juser.fz-juelich.de/record/17016},
}