TY  - JOUR
AU  - Mangiapia, G.
AU  - Vaccaro, M.
AU  - D'Errico, G.
AU  - Frielinghaus, H.
AU  - Radulescu, A.
AU  - Pipich, V.
AU  - Carnerup, A.M.
AU  - Paduano, L.
TI  - Cubosomes for Ruthenium complex delivery: formulation and characterization
JO  - Soft matter
VL  - 7
SN  - 1744-683X
CY  - Cambridge
PB  - Royal Society of Chemistry (RSC)
M1  - PreJuSER-18196
SP  - 10577 - 10580
PY  - 2011
N1  - The work was supported by MIUR (PRIN 2008-prot. 20087K9A2J). The authors thank the Forschungszentrum Julich for provision of beam time. SANS experiments were supported by the European Commission, NMI3 contract RII3-CT-2003-505925. The authors thank Prof. Viveka Alfredsson for critical assessment of the results obtained through Cryo-TEM images.
AB  - An amphiphilic ruthenium-based molecule (DOPURu) with potential antineoplastic activity has been synthesized, and its aggregation behavior in the presence of phospholipids has been investigated. A very rich variety of aggregates has been found, spanning from vesicles to cubic bicontinuous phases. Cubosomes here presented represent one of the first systems with potential use for medical therapy.
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000296388300011
DO  - DOI:10.1039/c1sm06323e
UR  - https://juser.fz-juelich.de/record/18196
ER  -