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@INBOOK{Musiani:186053,
      author       = {Musiani, Francesco and Rossetti, Giulia and Giorgetti,
                      Alejandro and Carloni, Paolo},
      title        = {{C}hemosensorial {G}-proteins-{C}oupled {R}eceptors: {A}
                      {P}erspective from {C}omputational {M}ethods},
      volume       = {805},
      address      = {Cham},
      publisher    = {Springer International Publishing},
      reportid     = {FZJ-2015-00154},
      isbn         = {978-3-319-02969-6 (print)},
      series       = {Advances in Experimental Medicine and Biology},
      pages        = {441 - 457},
      year         = {2014},
      comment      = {Protein Conformational Dynamics},
      booktitle     = {Protein Conformational Dynamics},
      abstract     = {G-protein coupled receptors (GPCRs) constitute the targets
                      of about 40 $\%$ of all the pharmaceutical drugs in the
                      market and, among other functions, a large portion of the
                      family detects odorants and a variety of tastant molecules.
                      Computational techniques are instrumental to understand
                      structure, dynamics and function of the cascades triggered
                      by these receptors. As an example, here we report our own
                      computational work aimed to dissect GPCR molecular
                      mechanisms for chemical senses. The implications of our work
                      for systems biology and for pharmacology are discussed.},
      cin          = {JSC / IAS-5 / INM-9},
      ddc          = {610},
      cid          = {I:(DE-Juel1)JSC-20090406 / I:(DE-Juel1)IAS-5-20120330 /
                      I:(DE-Juel1)INM-9-20140121},
      pnm          = {411 - Computational Science and Mathematical Methods
                      (POF2-411)},
      pid          = {G:(DE-HGF)POF2-411},
      typ          = {PUB:(DE-HGF)7},
      UT           = {WOS:000350417100018},
      doi          = {10.1007/978-3-319-02970-2_18},
      url          = {https://juser.fz-juelich.de/record/186053},
}