Contribution to a book

FZJ-2015-00154

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Chemosensorial G-proteins-Coupled Receptors: A Perspective from Computational Methods

Musiani, F. ; Rossetti, G.FZJ* ; Giorgetti, A. (Corresponding Author) ; Carloni, P.FZJ*

2014
Springer International Publishing Cham
ISBN: 978-3-319-02969-6 (print), 978-3-319-02970-2 (electronic)

This record in other databases:  

Please use a persistent id in citations: doi:10.1007/978-3-319-02970-2_18

Abstract: G-protein coupled receptors (GPCRs) constitute the targets of about 40 % of all the pharmaceutical drugs in the market and, among other functions, a large portion of the family detects odorants and a variety of tastant molecules. Computational techniques are instrumental to understand structure, dynamics and function of the cascades triggered by these receptors. As an example, here we report our own computational work aimed to dissect GPCR molecular mechanisms for chemical senses. The implications of our work for systems biology and for pharmacology are discussed.

---

Contributing Institute(s):

1. Jülich Supercomputing Center (JSC)
2. Computational Biomedicine (IAS-5)
3. Computational Biomedicine (INM-9)

Research Program(s):

1. 411 - Computational Science and Mathematical Methods (POF2-411) (POF2-411)

Appears in the scientific report 2014

---

Database coverage:
; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

---