% IMPORTANT: The following is UTF-8 encoded. This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.
@ARTICLE{Tappe:189099,
author = {Tappe, Wolfgang and Hofmann, Diana and Disko, Ulrich and
Köppchen, Stephan and Kummer, Sirgit and Vereecken, Harry},
title = {{A} novel isolated {T}errabacter-like bacterium can
mineralize2-aminopyrimidine, the principal metabolite of
microbialsulfadiazine degradation},
journal = {Biodegradation},
volume = {26},
number = {2},
issn = {0923-9820},
address = {Dordrecht},
publisher = {Springer Science + Business Media B.V},
reportid = {FZJ-2015-02312},
pages = {139-150},
year = {2015},
abstract = {Recently we showed that during thedegradation of
sulfadiazine (SDZ) by Microbacteriumlacus strain SDZm4 the
principal metabolite2-aminopyrimidine (2-AP) accumulated to
the samemolar amount in the culture as SDZ disappeared(Tappe
et al. Appl Environ Microbiol 79:2572–2577,2013). Although
2-AP is considered a recalcitrantagent, long-term lysimeter
experiments with 14Cpyrimidinelabeled SDZ ([14C]pyrSDZ)
provided indicationsfor substantial degradation of the
pyrimidinemoiety of the SDZ molecule. Therefore, we aimed
toenrich 2-AP degrading bacteria and isolated a pureculture
of a Terrabacter-like bacterium, denoted strain2APm3. When
provided with 14C-labeled SDZ, M.lacus strain SDZm4 degraded
[14C]pyrSDZ to [14C]2-AP. Resting cells of 2APm3 at a
concentration of5 9 106 cells ml-1 degraded 62 lM [14C]2-AP
tobelow the detection limit (0.6 lM) within 5
days.Disappearance of 2-AP resulted in the production of
atleast two transformation products (M1 and M2) withM2 being
identified as 2-amino-4-hydroxypyrimidine.After 36 days, the
transformation products disappearedand 83 $\%$ of the
applied [14C]2-AP radioactivitywas trapped as 14CO2. From
this we concludethat a consortium of two species should be
able toalmost completely degrade SDZ in soils.},
cin = {IBG-3},
ddc = {610},
cid = {I:(DE-Juel1)IBG-3-20101118},
pnm = {255 - Terrestrial Systems: From Observation to Prediction
(POF3-255) / 255 - Terrestrial Systems: From Observation to
Prediction (POF3-255)},
pid = {G:(DE-HGF)POF3-255 / G:(DE-HGF)POF3-255},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000352279300005},
doi = {10.1007/s10532-015-9722-9},
url = {https://juser.fz-juelich.de/record/189099},
}