TY  - JOUR
AU  - Timmermann, L.
AU  - Eggers, C.
AU  - Salimi Dafsari, H.
AU  - Pauls, K.
AU  - Barbe, M.
TI  - Morbus Parkinson: Aktuelle Standards in Diagnostik und Therapie
JO  - Fortschritte der Neurologie, Psychiatrie
VL  - 80
IS  - 10
SN  - 1439-3522
CY  - Stuttgart [u.a.]
PB  - Thieme
M1  - FZJ-2015-03501
SP  - 560 - 569
PY  - 2012
AB  - Idiopathic Parkinson’s disease is still a clinical diagnosis. However, modern imaging and nuclear techniques allow very early diagnosis and lead to higher security in the differential diagnosis between idiopathic Parkinson’s disease and atypical Parkinson syndromes. At early stages of the disease, modification of disease progression and symptom control are key factors of the therapy. Continuous dopaminergic stimulation is even more important at later stages with first fluctuations. In stages where conservative medical options have been exhausted continuous pump therapies with Duodopa and apomorphine are attractive options. Deep brain stimulation in the subthalamic nucleus has turned out in the last years, especially in younger patients, to be a highly successful treatment option. Deep drain stimulation requires, however, a close preoperative work-up and individual consideration of potential effects and side effects.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000310409200002
C6  - pmid:23033202
DO  - DOI:10.1055/s-0032-1312738
UR  - https://juser.fz-juelich.de/record/201196
ER  -