Journal Article

FZJ-2015-03501

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Morbus Parkinson: Aktuelle Standards in Diagnostik und Therapie

Timmermann, L. ; Eggers, C. ; Salimi Dafsari, H. ; Pauls, K. ; Barbe, M.FZJ*

2012
Thieme Stuttgart [u.a.]

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Please use a persistent id in citations: doi:10.1055/s-0032-1312738

Abstract: Idiopathic Parkinson’s disease is still a clinical diagnosis. However, modern imaging and nuclear techniques allow very early diagnosis and lead to higher security in the differential diagnosis between idiopathic Parkinson’s disease and atypical Parkinson syndromes. At early stages of the disease, modification of disease progression and symptom control are key factors of the therapy. Continuous dopaminergic stimulation is even more important at later stages with first fluctuations. In stages where conservative medical options have been exhausted continuous pump therapies with Duodopa and apomorphine are attractive options. Deep brain stimulation in the subthalamic nucleus has turned out in the last years, especially in younger patients, to be a highly successful treatment option. Deep drain stimulation requires, however, a close preoperative work-up and individual consideration of potential effects and side effects.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 333 - Pathophysiological Mechanisms of Neurological and Psychiatric Diseases (POF2-333) (POF2-333)

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Database coverage:
; BIOSIS Previews ; Current Contents - Clinical Medicine ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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