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@ARTICLE{Goulas:201251,
author = {Goulas, Alexandros and Bastiani, Matteo and Bezgin, Gleb
and Uylings, Harry B. M. and Roebroeck, Alard and Stiers,
Peter},
title = {{C}omparative {A}nalysis of the {M}acroscale {S}tructural
{C}onnectivity in the {M}acaque and {H}uman {B}rain},
journal = {PLoS Computational Biology},
volume = {10},
number = {3},
issn = {1553-7358},
address = {San Francisco, Calif.},
publisher = {Public Library of Science},
reportid = {FZJ-2015-03556},
pages = {e1003529},
year = {2014},
abstract = {The macaque brain serves as a model for the human brain,
but its suitability is challenged by unique human features,
including connectivity reconfigurations, which emerged
during primate evolution. We perform a quantitative
comparative analysis of the whole brain macroscale
structural connectivity of the two species. Our findings
suggest that the human and macaque brain as a whole are
similarly wired. A region-wise analysis reveals many
interspecies similarities of connectivity patterns, but also
lack thereof, primarily involving cingulate regions. We
unravel a common structural backbone in both species
involving a highly overlapping set of regions. This
structural backbone, important for mediating information
across the brain, seems to constitute a feature of the
primate brain persevering evolution. Our findings illustrate
novel evolutionary aspects at the macroscale connectivity
level and offer a quantitative translational bridge between
macaque and human research.},
cin = {INM-4 / JARA-BRAIN},
ddc = {570},
cid = {I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$},
pnm = {332 - Imaging the Living Brain (POF2-332)},
pid = {G:(DE-HGF)POF2-332},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000336509000040},
pubmed = {pmid:24676052},
doi = {10.1371/journal.pcbi.1003529},
url = {https://juser.fz-juelich.de/record/201251},
}