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| Hauptseite > Publikationsdatenbank > Comparative Analysis of the Macroscale Structural Connectivity in the Macaque and Human Brain > print |
| Hauptseite > Publikationsdatenbank > Comparative Analysis of the Macroscale Structural Connectivity in the Macaque and Human Brain > print |
| 001 | 201251 | ||
| 005 | 20210129215707.0 | ||
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| 100 | 1 | _ | |a Goulas, Alexandros |0 P:(DE-HGF)0 |b 0 |e Corresponding Author |
| 245 | _ | _ | |a Comparative Analysis of the Macroscale Structural Connectivity in the Macaque and Human Brain |
| 260 | _ | _ | |a San Francisco, Calif. |c 2014 |b Public Library of Science |
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| 520 | _ | _ | |a The macaque brain serves as a model for the human brain, but its suitability is challenged by unique human features, including connectivity reconfigurations, which emerged during primate evolution. We perform a quantitative comparative analysis of the whole brain macroscale structural connectivity of the two species. Our findings suggest that the human and macaque brain as a whole are similarly wired. A region-wise analysis reveals many interspecies similarities of connectivity patterns, but also lack thereof, primarily involving cingulate regions. We unravel a common structural backbone in both species involving a highly overlapping set of regions. This structural backbone, important for mediating information across the brain, seems to constitute a feature of the primate brain persevering evolution. Our findings illustrate novel evolutionary aspects at the macroscale connectivity level and offer a quantitative translational bridge between macaque and human research. |
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| 700 | 1 | _ | |a Uylings, Harry B. M. |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Roebroeck, Alard |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Stiers, Peter |0 P:(DE-HGF)0 |b 5 |
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