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@ARTICLE{Pauls:201392,
      author       = {Pauls, K. Amande M. and Hammesfahr, Sven and Moro, Elena
                      and Moore, A. Peter and Binder, Ellen and El Majdoub, Faycal
                      and Fink, Gereon R. and Sturm, Volker and Krauss, Joachim K.
                      and Maarouf, Mohammad and Timmermann, Lars},
      title        = {{D}eep brain stimulation in the ventrolateral
                      thalamus/subthalamic area in dystonia with head tremor},
      journal      = {Movement disorders},
      volume       = {29},
      number       = {7},
      issn         = {0885-3185},
      address      = {New York, NY},
      publisher    = {Wiley},
      reportid     = {FZJ-2015-03687},
      pages        = {953 - 959},
      year         = {2014},
      abstract     = {BackgroundPallidal deep brain stimulation (GPi-DBS)
                      effectively ameliorates idiopathic dystonia, although
                      approximately $15\%$ of patients respond insufficiently.
                      Although various thalamic and subthalamic targets have been
                      suggested for dystonic tremor, no systematic studies have
                      been published on thalamic DBS in dystonic tremor. We
                      assessed the effect of thalamic/subthalamic area DBS
                      (Th-DBS) on dystonic head tremor and dystonia in a
                      single-blind design.MethodsDystonic head tremor and dystonia
                      before and 3 months after surgery were quantified via
                      blinded video-ratings using the
                      Fahn-Tolosa-Marin-Tremor-Scale and the
                      Burke-Fahn-Marsden-Dystonia-Rating-Scale in seven patients
                      with idiopathic cervical or segmental dystonia, dystonic
                      head tremor, and bilateral Th-DBS. Pain, side effects,
                      adverse events, and stimulation parameters were
                      assessed.ResultsTh-DBS improved dystonic tremor and dystonia
                      (P < 0.05; $57.1\%$ and $70.4\%,$ respectively). Head
                      tremor amplitude and pain were also improved (P < 0.05;
                      $77.5\%$ and $90.0\%,$ respectively). Side effects included
                      dysarthria, gait disturbance, slowness of movement, and
                      weight gain.ConclusionDystonic head tremor and dystonia can
                      be improved with Th-DBS.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {333 - Pathophysiological Mechanisms of Neurological and
                      Psychiatric Diseases (POF2-333)},
      pid          = {G:(DE-HGF)POF2-333},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000337670600023},
      doi          = {10.1002/mds.25884},
      url          = {https://juser.fz-juelich.de/record/201392},
}