TY  - JOUR
AU  - Pham, Cong-Dat
AU  - Hartmann, Rudolf
AU  - Böhler, Philip
AU  - Stork, Björn
AU  - Wesselborg, Sebastian
AU  - Lin, Wenhan
AU  - Lai, Daowan
AU  - Proksch, Peter
TI  - Callyspongiolide, a Cytotoxic Macrolide from the Marine Sponge Callyspongia sp.
JO  - Organic letters
VL  - 16
IS  - 1
SN  - 1523-7052
CY  - Washington, DC
PB  - ACS
M1  - FZJ-2015-04434
SP  - 266 - 269
PY  - 2014
AB  - A novel macrolide, callyspongiolide, whose structure was determined by comprehensive analysis of the NMR and HRMS spectra, was isolated from the marine sponge Callyspongia sp. collected in Indonesia. The compound features a carbamate-substituted 14-membered macrocyclic lactone ring with a conjugated structurally unprecedented diene-ynic side chain terminating at a brominated benzene ring. Callyspongiolide showed strong cytotoxicity against human Jurkat J16 T and Ramos B lymphocytes.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000329472800069
C6  - pmid:24329175
DO  - DOI:10.1021/ol403241v
UR  - https://juser.fz-juelich.de/record/202145
ER  -