Journal Article FZJ-2015-05086

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No-carrier-added labeling of the neuroprotective Ebselen with selenium-73 and selenium-75

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2015
Wiley New York, NY [u.a.]

Journal of labelled compounds and radiopharmaceuticals 58(3), 141 - 145 () [10.1002/jlcr.3274]

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Abstract: Selenium-73 is a positron emitting non-standard radionuclide, which is suitable for positron emission tomography. A copper-catalyzed reaction allowed no-carrier-added labeling of the anti-inflammatory seleno-organic compound Ebselen with 73Se and 75Se under addition of sulfur carrier in a one-step reaction. The new authentically labeled radioselenium molecule is thus available for preclinical evaluation and positron emission tomography studies.

Classification:

Contributing Institute(s):
  1. Nuklearchemie (INM-5)
Research Program(s):
  1. 573 - Neuroimaging (POF3-573) (POF3-573)

Appears in the scientific report 2015
Database coverage:
Medline ; BIOSIS Previews ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection
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 Record created 2015-07-30, last modified 2021-01-29


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