Home > Publications database > No-carrier-added labeling of the neuroprotective Ebselen with selenium-73 and selenium-75 |
Journal Article | FZJ-2015-05086 |
; ; ;
2015
Wiley
New York, NY [u.a.]
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Please use a persistent id in citations: doi:10.1002/jlcr.3274
Abstract: Selenium-73 is a positron emitting non-standard radionuclide, which is suitable for positron emission tomography. A copper-catalyzed reaction allowed no-carrier-added labeling of the anti-inflammatory seleno-organic compound Ebselen with 73Se and 75Se under addition of sulfur carrier in a one-step reaction. The new authentically labeled radioselenium molecule is thus available for preclinical evaluation and positron emission tomography studies.
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