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@ARTICLE{Yakushenko:21511,
      author       = {Yakushenko, A. and Schnitker, J. and Wolfrum, B.},
      title        = {{P}rinted {C}arbon {M}icroelectrodes for {E}lectrochemical
                      {D}etection of {S}ingle {V}esicle {R}elease from {PC}12
                      {C}ells},
      journal      = {Analytical chemistry},
      volume       = {84},
      issn         = {0003-2700},
      address      = {Columbus, Ohio},
      publisher    = {American Chemical Society},
      reportid     = {PreJuSER-21511},
      pages        = {4613 - 4617},
      year         = {2012},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {We present a disposable system for recording
                      neurotransmitter release from individual cells in vitro. A
                      simple yet reliable microelectrode fabrication process is
                      introduced using screen-printed carbon paste. It allows
                      rapid fabrication of devices at low costs without standard
                      clean-room technology. We demonstrate functionality of the
                      system by real-time observation of vesicle release from
                      single PC12 (rat pheochromocytoma) cells. The cells are
                      cultured directly on the chip and can be used for immediate
                      or long-term in vitro experiments. Thus, our approach may
                      serve as a platform for pharmacological cell culture
                      studies.},
      keywords     = {Animals / Carbon: chemistry / Dopamine: analysis /
                      Electrochemical Techniques / Microelectrodes / Microscopy,
                      Electron, Scanning / PC12 Cells / Patch-Clamp Techniques /
                      Rats / Secretory Vesicles: metabolism / Carbon (NLM
                      Chemicals)},
      cin          = {ICS-8 / PGI-8 / JARA-FIT},
      ddc          = {540},
      cid          = {I:(DE-Juel1)ICS-8-20110106 / I:(DE-Juel1)PGI-8-20110106 /
                      $I:(DE-82)080009_20140620$},
      pnm          = {Grundlagen für zukünftige Informationstechnologien /
                      BioSoft: Makromolekulare Systeme und biologische
                      Informationsverarbeitung},
      pid          = {G:(DE-Juel1)FUEK412 / G:(DE-Juel1)FUEK505},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22509770},
      UT           = {WOS:000303965500052},
      doi          = {10.1021/ac300460s},
      url          = {https://juser.fz-juelich.de/record/21511},
}