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001 | 21865 | ||
005 | 20240619091014.0 | ||
024 | 7 | _ | |2 ISSN |a 0944-2952 |
024 | 7 | _ | |2 Handle |a 2128/4618 |
037 | _ | _ | |a PreJuSER-21865 |
041 | _ | _ | |a English |
082 | _ | _ | |a 500 |
100 | 1 | _ | |0 P:(DE-Juel1)VDB107378 |a Wehrse, Eckhard |b 0 |e Corresponding author |u FZJ |
245 | _ | _ | |a Stimulation of neuronal tissue using microelectrodes: experiments with a model system and simulations |
260 | _ | _ | |a Jülich |b Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag |c 2012 |
300 | _ | _ | |a III, 120 p. |
336 | 7 | _ | |0 PUB:(DE-HGF)19 |2 PUB:(DE-HGF) |a Master Thesis |
336 | 7 | _ | |0 2 |2 EndNote |a Thesis |
336 | 7 | _ | |2 DataCite |a Output Types/Supervised Student Publication |
336 | 7 | _ | |2 DRIVER |a masterThesis |
336 | 7 | _ | |2 ORCID |a SUPERVISED_STUDENT_PUBLICATION |
336 | 7 | _ | |2 BibTeX |a MASTERSTHESIS |
490 | 0 | _ | |a Berichte des Forschungszentrums Jülich |v 4352 |
500 | _ | _ | |a Record converted from JUWEL: 18.07.2013 |
500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
502 | _ | _ | |a Aachen, RWTH, Aachen, Diplomarbeit: Master Thesis |b Master (Univ.) |c RWTH Aachen |d 2012 |
520 | _ | _ | |a The electrical stimulation of neuronal tissue proofs to be a growing topic in current research both in physics, chemistry and in biomedical sciences [1] [2]. Insights of this field led to powerful techniques like Deep Brain Stimulation (DBS) as a standard therapy against idiopathic dystonia, Parkinson’s disease, essential tremor [3] [4] and severe forms of depression [5] [6] (see [7] for a list of reviews in the high frequency stimulation field of the last decade). A further field of application are medical prostheses like in the retina [8] or cochlea [9]. In theses cases an electrical stimulation is used to influence neuronal tissue in a designated manner, often by triggering action potentials. To excite the neuron (depolarisation), the stimulation pulse drives the extracellular space to (more) negative potentials leading to a smaller absolute value of the membrane potential, which remains still negative. If the potential difference over the axon membrane rises above a given value, an action potential occurs. The principle processes of generating a physiological action potential are well understood and reviewed in literature |
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655 | _ | 7 | |a Hochschulschrift |x Master Thesis (Univ.) |
856 | 4 | _ | |u https://juser.fz-juelich.de/record/21865/files/J%C2%A9%C6%A1l_4352_Wehrse.pdf |y OpenAccess |
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914 | 1 | _ | |y 2012 |
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