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@ARTICLE{Sun:22236,
author = {Sun, N. and Funke, S.A. and Willbold, D.},
title = {{M}irror image phage display - {G}enerating stable
therapeutically and diagnostically active peptides with
biotechnological means},
journal = {Journal of biotechnology},
volume = {161},
issn = {0168-1656},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {PreJuSER-22236},
pages = {121 - 125},
year = {2012},
note = {DW is supported by the CLIB-Graduate Cluster Industrial
Biotechnology. We thank Andrew Dingley for proofreading of
the manuscript.},
abstract = {Peptides are attracting increasing attention as
therapeutics. D-enantiomeric peptides are remarkably
resistant to in vivo proteolysis and elicit low immunogenic
responses when compared with the respective L-peptides.
Therefore, D-peptides can serve as therapeutic and early
diagnosis agents for drug development. Here we discuss the
application of mirror image phage display in pharmaceutical
biotechnology aiming to identify protease resistant
D-peptides with biotechnological approaches.},
keywords = {J (WoSType)},
cin = {ICS-6},
ddc = {540},
cid = {I:(DE-Juel1)ICS-6-20110106},
pnm = {Funktion und Dysfunktion des Nervensystems / BioSoft:
Makromolekulare Systeme und biologische
Informationsverarbeitung},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-Juel1)FUEK505},
shelfmark = {Biotechnology $\&$ Applied Microbiology},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22728425},
UT = {WOS:000307297500007},
doi = {10.1016/j.jbiotec.2012.05.019},
url = {https://juser.fz-juelich.de/record/22236},
}