Home > Publications database > Mirror image phage display - Generating stable therapeutically and diagnostically active peptides with biotechnological means > print

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|a 10.1016/j.jbiotec.2012.05.019
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082 _ _ |a 540
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|a Biotechnology & Applied Microbiology
100 1 _ |a Sun, N.
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|u FZJ
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245 _ _ |a Mirror image phage display - Generating stable therapeutically and diagnostically active peptides with biotechnological means
260 _ _ |a Amsterdam [u.a.]
|b Elsevier Science
|c 2012
300 _ _ |a 121 - 125
336 7 _ |a Journal Article
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440 _ 0 |a Journal of Biotechnology
|x 0168-1656
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|v 161
500 _ _ |3 POF3_Assignment on 2016-02-29
500 _ _ |a DW is supported by the CLIB-Graduate Cluster Industrial Biotechnology. We thank Andrew Dingley for proofreading of the manuscript.
520 _ _ |a Peptides are attracting increasing attention as therapeutics. D-enantiomeric peptides are remarkably resistant to in vivo proteolysis and elicit low immunogenic responses when compared with the respective L-peptides. Therefore, D-peptides can serve as therapeutic and early diagnosis agents for drug development. Here we discuss the application of mirror image phage display in pharmaceutical biotechnology aiming to identify protease resistant D-peptides with biotechnological approaches.
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|a Mirror image phage display
653 2 0 |2 Author
|a D-enantiomeric peptide
653 2 0 |2 Author
|a Pharmaceutical biotechnology
653 2 0 |2 Author
|a Drug discovery
700 1 _ |a Funke, S.A.
|b 1
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700 1 _ |a Willbold, D.
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773 _ _ |a 10.1016/j.jbiotec.2012.05.019
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856 7 _ |u http://dx.doi.org/10.1016/j.jbiotec.2012.05.019
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