Dissertation / PhD Thesis/Book

PreJuSER-26989

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Reaktionstechnische Untersuchungen zur L-Isoleucin Herstellung mit Corynebacterium glutamicum

Raeven, L. (Corresponding author)FZJ*

2000
Forschungszentrum Jülich GmbH Zenralbibliothek, Verlag Jülich

Please use a persistent id in citations: http://hdl.handle.net/2128/20635

Report No.: Juel-3798

Abstract: Thig obudvpnasentadhedeve!opnnentofmfed-ba1chprVmaas fo[U)e oroduodonof Uisokaminewith the Gram-positive bacbmhum Corynebaoterium glutamicum. BaaedoninventigsXions oonmerningthe transport of L-iso!euoine itvvaa discovered that production was energy Unnited . Further reaction engineering research showed that the energy Unnitmtion in indirect!y caused by a substrate Umitedion . With the aid of prindpa/ component ana!ymia citrate was identified as the significant !imitingpn)coas-varieb!eamd funhmr nas8archehovvedtha1this iadue to its rote auaniron-che!otor. By apeoiUua/!y feeding significant substrates Ike L-/euuine and substituting citrate by a more specific iron-oh g!ator 3.4-hvd,oxybenzoate, a L-iso!euo!ne concentration up to 220 mM with a space-time-yi&d of 5,4 mmof["h-/ and a integral yie!d of 14 % ( g/A) was accomplished

Note: Record converted from VDB: 12.11.2012
Note: Aachen, Techn. Hochsch., Diss., 2000

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Contributing Institute(s):

1. Institut für Biotechnologie (IBT)

Research Program(s):

1. Verfahrenstechnik zur mikrobiellen Gewinnung von Primärmetaboliten (41.40.0)

Appears in the scientific report 2000

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Database coverage:

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