Open Access

In vivo, the majority of nascent protein chains must begin folding during translation in order to obtain their native structure. While the importance of co-translational folding has become increasingly clear, the specific mechanisms underlying the coordination between the ribosome, nascent chain and molecular chaperones are still uncertain. [...]

Fluorescent protein (FP) variants have recently emerged as promising intracellular nitric oxide (NO) sensors based on NO-induced fluorescence loss due to cysteine S-nitrosylation - the covalent addition of a nitroso group to a cysteine thiol within a protein to form an S-nitrosothiol. Here, we investigate the mechanisms underlying this fluorescence loss using a combined experimental and computational approach. [...]

More than three decades ago, the inner membrane-associated protein of 30 kDa (IM30), also known as Vipp1, was identified in pea chloroplasts to bind to the chloroplast inner envelope membrane. IM30/Vipp1 is a membrane-associated and soluble stromal protein and is proposed to mediate vesicle formation. [...]

Enhanced weathering (EW) is proposed as a key strategy for climate change mitigation and carbon dioxide removal technology. Dissolution of silicate minerals enhances the alkalinity of the pore water, resulting at a shift of the carbonate system towards carbonate and bicarbonate, leading to higher dissolved inorganic carbon when the water is equilibrated with the atmosphere. [...]