TY  - JOUR
AU  - Bucciarelli, Saskia
AU  - Casal-Dujat, Lucía
AU  - De Michele, Cristiano
AU  - Sciortino, Francesco
AU  - Dhont, Jan K.G.
AU  - Bergenholtz, Johan
AU  - Farago, Bela
AU  - Schurtenberger, Peter
AU  - Stradner, Anna
TI  - Unusual Dynamics of Concentration Fluctuations in Solutions of Weakly Attractive Globular Proteins
JO  - The journal of physical chemistry letters
VL  - 6
IS  - 22
SN  - 1948-7185
CY  - Washington, DC
PB  - ACS
M1  - FZJ-2015-07695
SP  - 4470 - 4474
PY  - 2015
AB  - The globular protein γB-crystallin exhibits a complex phase behavior, where liquid–liquid phase separation characterized by a critical volume fraction ϕc = 0.154 and a critical temperature Tc = 291.8 K coexists with dynamical arrest on all length scales at volume fractions around ϕ ≈ 0.3–0.35, and an arrest line that extends well into the unstable region below the spinodal. However, although the static properties such as the osmotic compressibility and the static correlation length are in quantitative agreement with predictions for binary liquid mixtures, this is not the case for the dynamics of concentration fluctuations described by the dynamic structure factor S(q,t). Using a combination of dynamic light scattering and neutron spin echo measurements, we demonstrate that the competition between critical slowing down and dynamical arrest results in a much more complex wave vector dependence of S(q,t) than previously anticipated.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000365460700004
C6  - pmid:26505877
DO  - DOI:10.1021/acs.jpclett.5b02092
UR  - https://juser.fz-juelich.de/record/279816
ER  -