%0 Journal Article
%A Bolger, A. M.
%A Lohse, M.
%A Usadel, Björn
%T Trimmomatic: a flexible trimmer for Illumina sequence data
%J Bioinformatics
%V 30
%N 15
%@ 1460-2059
%C Oxford
%I Oxford Univ. Press
%M FZJ-2016-00423
%P 2114 - 2120
%D 2014
%X Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested. 
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000340049100004
%$ pmid:24695404
%R 10.1093/bioinformatics/btu170
%U https://juser.fz-juelich.de/record/280660