Journal Article FZJ-2016-00423

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Trimmomatic: a flexible trimmer for Illumina sequence data

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2014
Oxford Univ. Press Oxford

Bioinformatics 30(15), 2114 - 2120 () [10.1093/bioinformatics/btu170]

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Abstract: Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.

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Contributing Institute(s):
  1. Pflanzenwissenschaften (IBG-2)
Research Program(s):
  1. 582 - Plant Science (POF3-582) (POF3-582)

Appears in the scientific report 2015
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Medline ; Creative Commons Attribution CC BY 3.0 ; OpenAccess ; Allianz-Lizenz / DFG ; BIOSIS Previews ; Current Contents - Life Sciences ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection
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 Record created 2016-01-13, last modified 2021-01-29