000280660 001__ 280660 000280660 005__ 20210129221359.0 000280660 0247_ $$2doi$$a10.1093/bioinformatics/btu170 000280660 0247_ $$2ISSN$$a0266-7061 000280660 0247_ $$2ISSN$$a1367-4803 000280660 0247_ $$2ISSN$$a1367-4811 000280660 0247_ $$2ISSN$$a1460-2059 000280660 0247_ $$2Handle$$a2128/9693 000280660 0247_ $$2WOS$$aWOS:000340049100004 000280660 0247_ $$2altmetric$$aaltmetric:2232301 000280660 0247_ $$2pmid$$apmid:24695404 000280660 037__ $$aFZJ-2016-00423 000280660 041__ $$aEnglish 000280660 082__ $$a004 000280660 1001_ $$0P:(DE-HGF)0$$aBolger, A. M.$$b0 000280660 245__ $$aTrimmomatic: a flexible trimmer for Illumina sequence data 000280660 260__ $$aOxford$$bOxford Univ. Press$$c2014 000280660 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1452850334_31358 000280660 3367_ $$2DataCite$$aOutput Types/Journal article 000280660 3367_ $$00$$2EndNote$$aJournal Article 000280660 3367_ $$2BibTeX$$aARTICLE 000280660 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000280660 3367_ $$2DRIVER$$aarticle 000280660 500__ $$3POF3_Assignment on 2016-02-29 000280660 520__ $$aMotivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested. 000280660 536__ $$0G:(DE-HGF)POF3-582$$a582 - Plant Science (POF3-582)$$cPOF3-582$$fPOF III$$x0 000280660 588__ $$aDataset connected to CrossRef 000280660 7001_ $$0P:(DE-HGF)0$$aLohse, M.$$b1 000280660 7001_ $$0P:(DE-Juel1)145719$$aUsadel, Björn$$b2$$eCorresponding author$$ufzj 000280660 773__ $$0PERI:(DE-600)1468345-3$$a10.1093/bioinformatics/btu170$$gVol. 30, no. 15, p. 2114 - 2120$$n15$$p2114 - 2120$$tBioinformatics$$v30$$x1460-2059$$y2014 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.pdf$$yOpenAccess 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.gif?subformat=icon$$xicon$$yOpenAccess 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.jpg?subformat=icon-180$$xicon-180$$yOpenAccess 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.jpg?subformat=icon-640$$xicon-640$$yOpenAccess 000280660 8564_ $$uhttps://juser.fz-juelich.de/record/280660/files/Bioinformatics-2014-Bolger-2114-20.pdf?subformat=pdfa$$xpdfa$$yOpenAccess 000280660 909CO $$ooai:juser.fz-juelich.de:280660$$pdnbdelivery$$pVDB$$pdriver$$popen_access$$popenaire 000280660 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)145719$$aForschungszentrum Jülich GmbH$$b2$$kFZJ 000280660 9132_ $$0G:(DE-HGF)POF3-589H$$1G:(DE-HGF)POF3-580$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lKey Technologies for the Bioeconomy$$vAddenda$$x0 000280660 9131_ $$0G:(DE-HGF)POF3-582$$1G:(DE-HGF)POF3-580$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lKey Technologies for the Bioeconomy$$vPlant Science$$x0 000280660 9141_ $$y2015 000280660 915__ $$0LIC:(DE-HGF)CCBY3$$2HGFVOC$$aCreative Commons Attribution CC BY 3.0 000280660 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000280660 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences 000280660 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess 000280660 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bBIOINFORMATICS : 2014 000280660 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000280660 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index 000280660 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000280660 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5 000280660 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG 000280660 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000280660 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews 000280660 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000280660 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz 000280660 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000280660 9201_ $$0I:(DE-Juel1)IBG-2-20101118$$kIBG-2$$lPflanzenwissenschaften$$x0 000280660 980__ $$ajournal 000280660 980__ $$aVDB 000280660 980__ $$aUNRESTRICTED 000280660 980__ $$aI:(DE-Juel1)IBG-2-20101118 000280660 9801_ $$aUNRESTRICTED 000280660 9801_ $$aFullTexts