TY  - JOUR
AU  - Bolger, A. M.
AU  - Lohse, M.
AU  - Usadel, Björn
TI  - Trimmomatic: a flexible trimmer for Illumina sequence data
JO  - Bioinformatics
VL  - 30
IS  - 15
SN  - 1460-2059
CY  - Oxford
PB  - Oxford Univ. Press
M1  - FZJ-2016-00423
SP  - 2114 - 2120
PY  - 2014
AB  - Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested. 
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000340049100004
C6  - pmid:24695404
DO  - DOI:10.1093/bioinformatics/btu170
UR  - https://juser.fz-juelich.de/record/280660
ER  -