Journal Article

FZJ-2016-00483

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nudleotide polymorphisms

Rupp, O. ; Brinkrolf, K. (Corresponding author) ; Buerth, C. ; Kunigo, M. ; Schneider, J. ; Jaenicke, S. ; Goesmann, A. ; Pühler, A. ; Jaeger, K.-E.FZJ* ; Ernst, J. F.

2015
Wiley-VCH Weinheim

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Please use a persistent id in citations: doi:10.1016/j.jbiotec.2015.06.423

Abstract: The yeast Cyberlindnera jadinii is a close relative of Candida utilis that is being used in the food and feed industries. Here, we present the 12.7 Mb genome sequence of C. jadinii strain CBS 1600 generated by next generation sequencing. The deduced draft genome sequence consists of seven large scaffolds analogous to the seven largest chromosomes of C. utilis. An automated annotation of the C. jadinii genome identified 6147 protein-coding sequences. The level of ploidy for both genomes was analyzed by calling single nucleotide polymorphisms (SNPs) and was verified measuring nuclear DNA contents by florescence activated cell sorting (FACS). Both analyses determined the level of ploidy to diploid for C. jadinii and to triploid for C. utilis. However, SNP calling for C. jadinii also identified scaffold regions that seem to be haploid, triploid or tetraploid.

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Contributing Institute(s):

1. Institut für Molekulare Enzymtechnologie (HHUD) (IMET)

Research Program(s):

1. 89581 - Biotechnology (POF2-89581) (POF2-89581)

Appears in the scientific report 2015

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Database coverage:
; BIOSIS Previews ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; No Authors Fulltext ; SCOPUS ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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