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| 001 | 29267 | ||
| 005 | 20200402210503.0 | ||
| 024 | 7 | _ | |2 DOI |a 10.1209/epl/i2003-00311-6 |
| 024 | 7 | _ | |2 WOS |a WOS:000181456800019 |
| 024 | 7 | _ | |2 ISSN |a 0295-5075 |
| 037 | _ | _ | |a PreJuSER-29267 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 530 |
| 084 | _ | _ | |2 WoS |a Physics, Multidisciplinary |
| 100 | 1 | _ | |a Nguyen-Duong, C. J. |b 0 |0 P:(DE-HGF)0 |
| 245 | _ | _ | |a Surface anchoring reduces the lifetime of single specific bonds |
| 260 | _ | _ | |c 2003 |a Les Ulis |b EDP Sciences |
| 300 | _ | _ | |a 845 - 851 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |a Europhysics Letters |x 0295-5075 |0 1996 |y 6 |v 61 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a We investigated the force-induced dissociation of single specific bonds between protein A and immunoglobulin G. In these experiments both proteins were tethered to microbeads. Piconewton forces were applied by means of an ultrasoft spring. Upon bond formation the thermal fluctuations of this soft spring were reduced. This resulted in a sizeable contribution to the free enthalpy of bonding. Including this effect we calculated the relation between the lifetime of bonds connecting both microbeads and the lifetime of the bond between free molecules. We found that in the first case the lifetime depended on the stiffness of the force probe. Moreover, the lifetime was reduced by almost two orders of magnitude. Both predictions were verified in our experiments. |
| 536 | _ | _ | |a Neurowissenschaften |c L01 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK255 |x 0 |
| 536 | _ | _ | |a Kondensierte Materie |c M02 |0 G:(DE-Juel1)FUEK242 |x 1 |
| 588 | _ | _ | |a Dataset connected to Web of Science |
| 650 | _ | 7 | |a J |2 WoSType |
| 700 | 1 | _ | |a Koch, K.-W. |b 1 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Merkel, R. |b 2 |u FZJ |0 P:(DE-Juel1)128833 |
| 773 | _ | _ | |a 10.1209/epl/i2003-00311-6 |g Vol. 61, p. 845 - 851 |0 PERI:(DE-600)1465366-7 |q 61<845 - 851 |p 845 - 851 |t epl |v 61 |y 2003 |x 0295-5075 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1209/epl/i2003-00311-6 |
| 909 | C | O | |o oai:juser.fz-juelich.de:29267 |p VDB |
| 913 | 1 | _ | |k L01 |v Neurowissenschaften |l Funktion und Dysfunktion des Nervensystems |b Leben |0 G:(DE-Juel1)FUEK255 |x 0 |
| 913 | 1 | _ | |k M02 |v Kondensierte Materie |l Kondensierte Materie |b Materie |0 G:(DE-Juel1)FUEK242 |x 1 |
| 914 | 1 | _ | |y 2003 |
| 915 | _ | _ | |a No Peer review |0 StatID:(DE-HGF)0020 |2 StatID |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 920 | 1 | _ | |k IBI-1 |l Zelluläre Signalverarbeitung |d 31.12.2006 |g IBI |0 I:(DE-Juel1)VDB57 |x 1 |
| 920 | 1 | _ | |k ISG-4 |l Institut für biologisch-anorganische Grenzflächen |d 31.12.2001 |g ISG |0 I:(DE-Juel1)VDB44 |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)25867 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-4-20110106 |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-7-20110106 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-1-20200312 |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-2-20200312 |
| 981 | _ | _ | |a I:(DE-Juel1)ICS-4-20110106 |
| 981 | _ | _ | |a I:(DE-Juel1)ICS-7-20110106 |
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