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@ARTICLE{Li:29559,
author = {Li, Y. L. and Friedland, W. and Pomplun, E. and Jacob, P.
and Paretzke, H. G. and Lassmann, M. and Reiners, C.},
title = {{T}rack structures and dose distributions from decays of
{I}-131 and {I}-125 in and around water spheres simulating
micrometastases of differentiated thyroid cancer},
journal = {Radiation research},
volume = {156},
issn = {0033-7587},
address = {Great Falls, Va.},
publisher = {Radiation Research Society},
reportid = {PreJuSER-29559},
pages = {419 - 429},
year = {2001},
note = {Record converted from VDB: 12.11.2012},
abstract = {The disintegration of the radionuclides I-131 and I-125 and
the subsequent charged-particle tracks left behind in water
(as a model substance for a biological cell) are simulated
by the Monte Carlo track structure simulation code PARTRAC,
using new inelastic electron scattering cross sections for
condensed water. Every photon and electron emitted was
followed in detail, event by event, down to 10 eV. From the
spatial information on the track structures, absorbed dose
distributions per I-131 and I-121 decay were calculated in
and around water spheres simulating micrometastases as well
as in the tissue surrounding such metastases. These
radionuclides were assumed to be distributed uniformly
inside spheres of different diameters (0.01, 0.03, 0.1, 0.3,
1.0 and 3.0 nun). The respective electron degradation
spectra, the nearest-neighbor distance distributions between
inelastic events, and the distance distributions for all
activations for both iodine radionuclides were calculated.
The absorbed fractions of the initial electron energies,
absorbed doses and energy depositions, and single-event
distributions, F-1(epsilon), inside the six water spheres
described above and in the surrounding tissue were also
calculated. The absorbed doses per decay inside the six
water spheres, i.e., the calculated S values (listed from
0.01 to 3.0 nun), were 6.8 x 10(-4), 7.2 x 10(-5), 5.5 x
10(-6), 4.9 x 10(-7), 3.1 x 10(-8) and 1.8 x 10(-9) Gy
Bq(-1) s(-1) for I-131, and 3.4 x 10(-3), 1.7 x 10(-4), 5.1
x 10(-6), 2.0 x 10(-1), 5.6 x 10(-9) and 2.2 x 10(-11) Gy
Bq(-1) s(-1) for I-125. It is concluded that in the
treatment of thyroid cancer, the geometrical track structure
properties of I-125 might be superior to those of I-131 in
micrometastases with diameters less than 0.1 nun; however,
in this medical context, many other factors also have to be
considered. (C) 2001 by Radiation Research Society.},
keywords = {J (WoSType)},
cin = {ASS},
ddc = {610},
cid = {I:(DE-Juel1)VDB60},
pnm = {Begleitende Arbeiten zur Umgebungsüberwachung},
pid = {G:(DE-Juel1)FUEK99},
shelfmark = {Biology / Biophysics / Radiology, Nuclear Medicine $\&$
Medical Imaging},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000171327000010},
doi = {10.1667/0033-7587(2001)156[0419:TSADDF]2.0.CO;2},
url = {https://juser.fz-juelich.de/record/29559},
}