Journal Article

PreJuSER-40334

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Effects of germini surfactants on egg phosphatidylcholine bilayers in the fluid lamellar phase

Dubnichkova, M. ; Yaradaykin, S. ; Lacko, I. ; Devinsky, F. ; Gordeliy, I. L.FZJ* ; Balgovy, P.

2004
Elsevier Science Amsterdam [u.a.]

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Please use a persistent id in citations: doi:10.1016/j.colsurfb.2003.12.009

Abstract: The influence of 1,4-butanediamonium-N,N'-dialkyl-N,N,N',N'-tetramethyl dibromides (CmA, m = 7-16 is the number of alkyl carbons) on the egg yolk phosphatidylcholine (EYPC) bilayer thickness and lipid surface area at the bilayer-aqueous phase interface is studied using X-ray diffraction on fluid lamellar CmA + EYPC + H2O phases as a function of CmA:EYPC and H2O:EYPC molar ratios and the alkyl chain length m. At the constant CmA:EYPC = 0.4 and H2O:EYPC = 18 molar ratios, the CmA induced bilayer thickness decrease shows a minimum and the lipid surface area increase a maximum at the alkyl chain length m = 9. The obtained results are discussed in the context of a structural perturbation model of the cut-off effect in biological potencies of surfactants which occurs when increasing the alkyl substituent chain length above the critical value.

Keyword(s): Egg Yolk: metabolism (MeSH) ; Lipid Bilayers: chemistry (MeSH) ; Lipids: chemistry (MeSH) ; Liposomes: chemistry (MeSH) ; Models, Chemical (MeSH) ; Models, Statistical (MeSH) ; Phosphatidylcholines: chemistry (MeSH) ; Scattering, Radiation (MeSH) ; X-Ray Diffraction (MeSH) ; Lipid Bilayers ; Lipids ; Liposomes ; Phosphatidylcholines ; J ; lipid bilayer (auto) ; lamellar phase (auto) ; gemini surfactants (auto) ; x-ray diffraction (auto)

Note: Record converted from VDB: 12.11.2012

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Contributing Institute(s):

1. Biologische Strukturforschung (IBI-2)

Research Program(s):

1. Neurowissenschaften (L01)

Appears in the scientific report 2004

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