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| 001 | 45561 | ||
| 005 | 20200423204120.0 | ||
| 024 | 7 | _ | |a pmid:16851866 |2 pmid |
| 024 | 7 | _ | |a 10.1021/jp044980b |2 DOI |
| 024 | 7 | _ | |a WOS:000228419100088 |2 WOS |
| 024 | 7 | _ | |a 2128/706 |2 Handle |
| 037 | _ | _ | |a PreJuSER-45561 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 530 |
| 084 | _ | _ | |2 WoS |a Chemistry, Physical |
| 100 | 1 | _ | |a Koenig, B. W. |b 0 |u FZJ |0 P:(DE-Juel1)132009 |
| 245 | _ | _ | |a Lipid ethanol interaction studied by NMR on bicelles |
| 260 | _ | _ | |a Washington, DC |b Soc. |c 2005 |
| 300 | _ | _ | |a 7540 - 7547 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |a Journal of Physical Chemistry B |x 1520-6106 |0 3694 |v 109 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a The interaction of ethanol with phospholipids was studied in bicelles at a physiologically relevant ethanol concentration of 20 mM and a lipid content of 14 wt % by high-resolution NMR. Transient association of ethanol with magnetically aligned bicelles imparts a small degree of anisotropy to the solute. This anisotropy allows detection of residual (1)H-(1)H and (1)H-(13)C dipolar couplings, which are superimposed on scalar couplings. Residual (2)H NMR quadrupole splittings of isotope-labeled ethanol were measured as well. The analysis of residual tensorial interactions yielded information on the orientation and motions of ethanol in the membrane-bound state. The fraction of phosphatidylcholine-bound ethanol was determined independently by gas chromatography and NMR. About 4% of ethanol is bound to phosphatidylcholine at a bicelle concentration of 14 wt % at 40 degrees C. Free and bound ethanol are in rapid exchange. The lifetime of ethanol association with phosphatidylcholine membranes is of the order of a few nanoseconds. |
| 536 | _ | _ | |a Neurowissenschaften |c L01 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK255 |x 0 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Chemistry, Physical: methods |
| 650 | _ | 2 | |2 MeSH |a Chromatography, Gas |
| 650 | _ | 2 | |2 MeSH |a Dimyristoylphosphatidylcholine: chemistry |
| 650 | _ | 2 | |2 MeSH |a Ethanol: chemistry |
| 650 | _ | 2 | |2 MeSH |a Lipid Bilayers |
| 650 | _ | 2 | |2 MeSH |a Lipids: chemistry |
| 650 | _ | 2 | |2 MeSH |a Magnetic Resonance Spectroscopy |
| 650 | _ | 2 | |2 MeSH |a Molecular Conformation |
| 650 | _ | 2 | |2 MeSH |a Phosphatidylcholines: chemistry |
| 650 | _ | 2 | |2 MeSH |a Phospholipids: chemistry |
| 650 | _ | 2 | |2 MeSH |a Time Factors |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Lipid Bilayers |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Lipids |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Phosphatidylcholines |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Phospholipids |
| 650 | _ | 7 | |0 13699-48-4 |2 NLM Chemicals |a Dimyristoylphosphatidylcholine |
| 650 | _ | 7 | |0 64-17-5 |2 NLM Chemicals |a Ethanol |
| 650 | _ | 7 | |a J |2 WoSType |
| 700 | 1 | _ | |a Gawrisch, K. |b 1 |0 P:(DE-HGF)0 |
| 773 | _ | _ | |a 10.1021/jp044980b |g Vol. 109, p. 7540 - 7547 |p 7540 - 7547 |q 109<7540 - 7547 |0 PERI:(DE-600)2006039-7 |t The @journal of physical chemistry |v 109 |y 2005 |x 1520-6106 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1021/jp044980b |u http://hdl.handle.net/2128/706 |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/45561/files/69735.pdf |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/45561/files/69735.jpg?subformat=icon-1440 |x icon-1440 |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/45561/files/69735.jpg?subformat=icon-180 |x icon-180 |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/45561/files/69735.jpg?subformat=icon-640 |x icon-640 |y OpenAccess |
| 909 | C | O | |o oai:juser.fz-juelich.de:45561 |p openaire |p open_access |p driver |p VDB |p dnbdelivery |
| 913 | 1 | _ | |k L01 |v Neurowissenschaften |l Funktion und Dysfunktion des Nervensystems |b Leben |0 G:(DE-Juel1)FUEK255 |x 0 |
| 914 | 1 | _ | |y 2005 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 915 | _ | _ | |2 StatID |0 StatID:(DE-HGF)0510 |a OpenAccess |
| 920 | 1 | _ | |k IBI-2 |l Biologische Strukturforschung |d 31.12.2006 |g IBI |0 I:(DE-Juel1)VDB58 |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)69735 |
| 980 | 1 | _ | |a FullTexts |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a JUWEL |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)ISB-2-20090406 |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
| 980 | _ | _ | |a FullTexts |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
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